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- Dodgson, Jerry B., et al. Show all 4 Authors
- Animal biotechnology 2016 v.27 no.4 pp. 238-244
- Mardivirus; Marek disease; alleles; alternative splicing; chickens; exons; gel electrophoresis; genetic resistance; inbred lines; isomers; mutation; nucleotides; phenotype; polymerase chain reaction; sequence analysis; viruses
- ... Utilizing RNA-seq data, 1,574 candidate genes with alternative splicing were previously identified between two chicken lines that differ in Marek’s disease (MD) genetic resistance under control and Marek’s disease virus infection conditions. After filtering out 1,530 genes with splice variants in the first or last exon, 44 genes were screened for possible exon loss or gain using PCR and gel electr ...
- Dodgson, Jerry B., et al. Show all 32 Authors
- G3 2017 v.7 no.1 pp. 109-117
- Gallus gallus; animal models; autosomes; bacterial artificial chromosomes; chickens; gene dosage; genes; genome assembly; nucleotide sequences
- ... The importance of the Gallus gallus (chicken) as a model organism and agricultural animal merits a continuation of sequence assembly improvement efforts. We present a new version of the chicken genome assembly (Gallus_gallus-5.0; GCA_000002315.3), built from combined long single molecule sequencing technology, finished BACs, and improved physical maps. In overall assembled bases, we see a gain of ...
- Dodgson, Jerry B., et al. Show all 72 Authors
- Meleagris gallopavo; Taeniopygia guttata; chickens; chromosomes; cost effectiveness; evolution; gene deletion; genes; genetic variation; genome assembly; heterozygosity; high-throughput nucleotide sequencing; immune system; mammals; models; non-coding RNA; nucleotide sequences; quantitative traits; turkeys
- ... A synergistic combination of two next-generation sequencing platforms with a detailed comparative BAC physical contig map provided a cost-effective assembly of the genome sequence of the domestic turkey (Meleagris gallopavo). Heterozygosity of the sequenced source genome allowed discovery of more than 600,000 high quality single nucleotide variants. Despite this heterozygosity, the current genome ...
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