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- Duarte, Trevor T., et al. Show all 8 Authors
- Infection and immunity 2008 v.76 no.7 pp. 2939-2949
- Giardia lamblia; biosynthesis; encystment; endocytosis; endoplasmic reticulum; eukaryotic cells; gene duplication; gene expression regulation; genes; giardiasis; humans; phylogeny; prokaryotic cells; serine C-palmitoyltransferase; sphingolipids; transcription (genetics); trophozoites
- ... Although encystation (cyst formation) is important for the survival of Giardia lamblia outside its human host, the molecular events that prompt encystation have not been fully elucidated. Here, we demonstrate that sphingolipids (SLs), which are important for the growth and differentiation of many eukaryotes, play key roles in giardial encystation. Transcriptional analyses showed that only three ge ...
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