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- Emami, Armaghan, et al. Show all 4 Authors
- Nutrition and cancer 2010 v.62 no.5 pp. 622-629
- lipid peroxidation; ascorbic acids; tocopherols; oxidation; acrolein; antineoplastic agents
- ... Oxidation of polyunsaturated fatty acids (PUFAs) releases α,β-unsaturated aldehydes that modify deoxyguanosine (dG) to form cyclic 1,N2-propanodeoxyguanosine adducts. One of the major adducts detected in vivo is acrolein (Acr)-derived 1,N2-propanodeoxyguanosine (Acr-dG). We used a chemical model system to examine the effects of 4 antioxidants known to inhibit fatty acid oxidation on the formation ...
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