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- Erturhan, Sakip, et al. Show all 9 Authors
- Molecular biology reports 2015 v.42 no.2 pp. 507-516
- bladder; carcinoma; chromosomes; epigenetics; exons; heterozygosity; mutation; oncogenes; patients; promoter regions; transcription factors; tumor suppressor genes; urinary bladder neoplasms
- ... Cancer is a consequence of accumulation of genetic and epigenetic alterations in the cell which can lead to activation of oncogenes or inactivation of tumor suppressor genes (TSG). Since members of ING family were discovered as TSGs in different cancer types, it was aimed to analyze the chromosome 13q33-34 region, ING1 and p53 genes in bladder cancer. 30 paired normal and tumor tissues were invest ...