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- Fazekas de St Groth, Barbara, et al. Show all 7 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2011 v.108 no.44 pp. 18049-18054
- Langerhans cells; T-lymphocytes; adjuvants; antigen presentation; basement membrane; cytoplasm; immune response; immunosuppression (physiological); interleukin-12; microorganisms; pathogens
- ... Antigen-dependent interactions between T lymphocytes and dendritic cells (DCs) can produce two distinct outcomes: tolerance and immunity. It is generally considered that all DC subsets are capable of supporting both tolerogenic and immunogenic responses, depending on their exposure to activating signals. Here, we tested whether epidermal Langerhans cells (LCs) can support immunogenic responses in ...
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