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1. Cardiac function and feed efficiency: Increased right-heart workload in feed inefficient beef cattle
- Author:
- Flávio S. Schenkel, et al. ; Jasper C. Munro; Peter W. Physick-Sheard; W. Glen Pyle; Stephen P. Miller; Yuri R. Montanholi; Show all 6 Authors
- Source:
- Livestock science 2019 v.229 pp. 159-169
- ISSN:
- 1871-1413
- Subject:
- beef cattle; blood volume; brain; bulls; calcium; carcass composition; cardiac output; cattle feeds; environmental impact; enzyme activity; feed conversion; feed intake; feed prices; heart; heart rate; heifers; myosin light chains; protein phosphorylation; regression analysis; slaughterhouses; steers
- Abstract:
- ... Heart rate (HR) during rest and stress as a beef cattle feed efficiency proxy (residual feed intake; RFI) has potential to reduce environmental impact and feed costs. A broader understanding of the association between the cardiac system and feed efficiency is needed before commercial application of heart rate as a feed efficiency proxy can occur. Objectives of this study were to assess the relatio ...
- DOI:
- 10.1016/j.livsci.2019.09.029
- https://doi.org/10.1016/j.livsci.2019.09.029
- Author:
- Flávio S. Schenkel, et al. ; Mohammed N. Boareki; Luiz F. Brito; Ángela Cánovas; Vern Osborne; Show all 5 Authors
- Source:
- Canadian journal of animal science 2020 v.101 no.1 pp. 134-142
- ISSN:
- 0008-3984
- Subject:
- animal science; ewes; heritability; litter size; multiple trait selection; selection index; selection response
- Abstract:
- ... The goal of this study was to estimate genetic parameters and predict direct and correlated response to selection for lamb growth traits and ewe reproductive traits, based on single-trait selection or combining multiple traits in an optimum index that targets total litter post-weaning weight in the first lambing as the main selection goal. Heritability estimates ranged from 0.04 to 0.19. Genetic c ...
- DOI:
- 10.1139/cjas-2019-0152
- https://doi.org/10.1139/cjas-2019-0152
- Author:
- Flávio S. Schenkel, et al. ; Katarzyna Stachowicz; Luiz F. Brito; Hinayah R. Oliveira; Stephen P. Miller; Show all 5 Authors
- Source:
- Canadian journal of animal science 2018 v.98 no.4 pp. 741-749
- ISSN:
- 1918-1825
- Subject:
- Polypay; Romanov; breeding programs; data collection; effective population size; genetic variation; genome; inbreeding; inbreeding coefficient; pedigree; selection response; sheep; Canada
- Abstract:
- ... The loss of genetic variability in a population will drastically affect the success of a breeding program by reducing selection response and fitness and, consequently, affecting reproduction, resilience, and production efficiency. The objective of this study was to perform an in-depth analysis of the pedigree of the Canadian sheep breeds to assess the levels of inbreeding, effective population siz ...
- DOI:
- 10.1139/cjas-2017-0187
- https://doi.org/10.1139/cjas-2017-0187
- Author:
- Flávio S. Schenkel, et al. ; Mario L. Piccoli; Luiz F. Brito; José Braccini; Hinayah R. Oliveira; Fernando F. Cardoso; Vanerlei M. Roso; Mehdi Sargolzaei; Show all 8 Authors
- Source:
- Livestock science 2020 v.231 pp. 103864
- ISSN:
- 1871-1413
- Subject:
- Hereford; beef cattle; birth weight; body conformation; body size; breeding programs; breeding value; early development; genetic markers; genomics; genotype; livestock breeding; marker-assisted selection; pedigree; phenotype; pigmentation; prediction; prepuce; regression analysis; ticks; weight gain
- Abstract:
- ... Various strategies to the use of genetic markers in genetic evaluations have been proposed and substantial genetic progress has been achieved in livestock breeding programs by incorporating genomic information. However, the implementation of genomic selection in beef cattle breeds, especially in composites, adapted to tropical and sub-tropical conditions, is well behind other cattle breeds. Altern ...
- DOI:
- 10.1016/j.livsci.2019.103864
- https://doi.org/10.1016/j.livsci.2019.103864
- Author:
- Flávio S. Schenkel, et al. ; Valdecy Aparecida Rocha da Cruz; Luiz F. Brito; Hinayah Rojas de Oliveira; Mohsen Jafarikia; Zeny Feng; Show all 6 Authors
- Source:
- Livestock science 2019 v.220 pp. 173-179
- ISSN:
- 1871-1413
- Subject:
- backfat; breeding value; fat thickness; genomics; genotype; genotyping; litter size; marker-assisted selection; phenotype; piglets; pork industry; prediction; single nucleotide polymorphism
- Abstract:
- ... Genotyping costs and the large number of selection candidates are major factors that inhibit the application of genomic selection in the swine industry and other small-sized livestock species. In order to reduce genotyping costs and increase the uptake of genomic selection, a possible strategy is to genotype animals with an affordable low-density (LD) SNP panel and, then accurately impute the LD p ...
- DOI:
- 10.1016/j.livsci.2018.12.027
- https://doi.org/10.1016/j.livsci.2018.12.027
- Author:
- Flávio S. Schenkel, et al. ; Raphael Boré; Luiz F. Brito; Mohsen Jafarikia; Alban Bouquet; Laurence Maignel; Brian Sullivan; Show all 7 Authors
- Source:
- Canadian journal of animal science 2018 v.98 no.4 pp. 809-817
- ISSN:
- 1918-1825
- Subject:
- breeding value; genetic variation; genomics; genotyping; landraces; linkage disequilibrium; marker-assisted selection; prediction; principal component analysis; purebreds; single nucleotide polymorphism; swine; swine breeds
- Abstract:
- ... Combining reference populations from different countries and breeds could be an affordable way to enlarge the size of the reference populations for genomic prediction of breeding values. Therefore, the main objectives of this study were to assess the genetic diversity within and between two Canadian and French pig breeds (Landrace and Yorkshire) and the genomic relatedness among populations to eva ...
- DOI:
- 10.1139/cjas-2017-0103
- https://doi.org/10.1139/cjas-2017-0103
- Author:
- Flávio S. Schenkel, et al. ; Steven G. Larmer; Mehdi Sargolzaei; Luiz F. Brito; Ricardo V. Ventura; Show all 5 Authors
- Source:
- BMC genetics 2017 v.18 no.1 pp. 120
- ISSN:
- 1471-2156
- Subject:
- algorithms; beef cattle; crossbreds; dairy breeds; dairy cattle; genome; genomics; genotyping; haplotypes; high-throughput nucleotide sequencing; linear models; livestock and meat industry; pedigree; prediction; purebreds; single nucleotide polymorphism
- Abstract:
- ... BACKGROUND: Accurate imputation plays a major role in genomic studies of livestock industries, where the number of genotyped or sequenced animals is limited by costs. This study explored methods to create an ideal reference population for imputation to Next Generation Sequencing data in cattle. METHODS: Methods for clustering of animals for imputation were explored, using 1000 Bull Genomes Project ...
- DOI:
- 10.1186/s12863-017-0588-1
- PubMed:
- 29281958
- PubMed Central:
- PMC5746022
- https://doi.org/10.1186/s12863-017-0588-1
- Author:
- Flávio S. Schenkel, et al. ; Daniela A. Grossi; Mohsen Jafarikia; Luiz F. Brito; Marcos E. Buzanskas; Mehdi Sargolzaei; Show all 6 Authors
- Source:
- BMC genetics 2017 v.18 no.1 pp. 6
- ISSN:
- 1471-2156
- Subject:
- Duroc; breeding value; crossbreds; effective population size; genetic variation; genome; genotyping; herds; inbreeding; landraces; linkage disequilibrium; marker-assisted selection; population structure; purebreds; single nucleotide polymorphism; swine; Canada
- Abstract:
- ... BACKGROUND: Knowledge on the levels of linkage disequilibrium (LD) across the genome, persistence of gametic phase between breed pairs, genetic diversity and population structure are important parameters for the successful implementation of genomic selection. Therefore, the objectives of this study were to investigate these parameters in order to assess the feasibility of a multi-herd and multi-br ...
- DOI:
- 10.1186/s12863-017-0473-y
- PubMed:
- 28109261
- PubMed Central:
- PMC5251314
- https://doi.org/10.1186/s12863-017-0473-y
- Author:
- Flávio S. Schenkel, et al. ; Mario L. Piccoli; Luiz F. Brito; José Braccini; Fernando F. Cardoso; Mehdi Sargolzaei; Show all 6 Authors
- Source:
- BMC genetics 2017 v.18 no.1 pp. 2
- ISSN:
- 1471-2156
- Subject:
- Hereford; beef cattle; breeding programs; breeding value; cattle breeding; equations; genomics; genotype; genotyping; marker-assisted selection; prediction; prices; single nucleotide polymorphism; statistical models
- Abstract:
- ... BACKGROUND: Genomic selection (GS) has played an important role in cattle breeding programs. However, genotyping prices are still a challenge for implementation of GS in beef cattle and there is still a lack of information about the use of low-density Single Nucleotide Polymorphisms (SNP) chip panels for genomic predictions in breeds such as Brazilian Braford and Hereford. Therefore, this study in ...
- DOI:
- 10.1186/s12863-017-0475-9
- PubMed:
- 28100165
- PubMed Central:
- PMC5241971
- https://doi.org/10.1186/s12863-017-0475-9
- Author:
- Flávio S. Schenkel, et al. ; Luiz F. Brito; Shannon M. Clarke; John C. McEwan; Stephen P. Miller; Natalie K. Pickering; Wendy E. Bain; Ken G. Dodds; Mehdi Sargolzaei; Show all 9 Authors
- Source:
- BMC genetics 2017 v.18 no.1 pp. 7
- ISSN:
- 1471-2156
- Subject:
- breeding programs; breeding value; carcass quality; composite breeds; genetic improvement; genetic variation; geneticists; genotyping; industry; marker-assisted selection; meat quality; phenotype; prediction; sheep; sheep breeds; single nucleotide polymorphism; sires; New Zealand
- Abstract:
- ... BACKGROUND: New Zealand has some unique Terminal Sire composite sheep breeds, which were developed in the last three decades to meet commercial needs. These composite breeds were developed based on crossing various Terminal Sire and Maternal breeds and, therefore, present high genetic diversity compared to other sheep breeds. Their breeding programs are focused on improving carcass and meat qualit ...
- DOI:
- 10.1186/s12863-017-0476-8
- PubMed:
- 28122512
- PubMed Central:
- PMC5267438
- https://doi.org/10.1186/s12863-017-0476-8
- Author:
- Flávio S. Schenkel, et al. ; Mario L. Piccoli; Luiz F. Brito; José Braccini; Fernanda V. Brito; Fernando F. Cardoso; Jaime A. Cobuci; Mehdi Sargolzaei; Show all 8 Authors
- Source:
- Canadian journal of animal science 2018 v.98 no.3 pp. 565-575
- ISSN:
- 1918-1825
- Subject:
- beef cattle; breeding value; bulls; cattle production; females; genomics; grazing; mixing; parents; pedigree; phenotype; prediction; production technology; statistical analysis
- Abstract:
- ... The statistical methods used in the genetic evaluations are a key component of the process and can be best compared by using simulated data. The latter is especially true in grazing beef cattle production systems, where the number of proven bulls with highly reliable estimated breeding values is limited to allow for a trustworthy validation of genomic predictions. Therefore, we simulated data for ...
- DOI:
- 10.1139/cjas-2017-0176
- https://doi.org/10.1139/cjas-2017-0176
- Author:
- Flávio S. Schenkel, et al. ; Luiz F. Brito; John C. McEwan; Stephen P. Miller; Natalie K. Pickering; Wendy E. Bain; Ken G. Dodds; Shannon M. Clarke; Show all 8 Authors
- Source:
- BMC genetics 2017 v.18 no.1 pp. 25
- ISSN:
- 1471-2156
- Subject:
- sires; marker-assisted selection; composite breeds; haplotypes; phenotype; sheep; genome-wide association study; principal component analysis; single nucleotide polymorphism; linkage disequilibrium; Texel; effective population size; inbreeding; mixed breeds; genotyping; genetic variation; population structure; breeding value; prediction; New Zealand
- Abstract:
- ... BACKGROUND: Knowledge about the genetic diversity of a population is a crucial parameter for the implementation of successful genomic selection and conservation of genetic resources. The aim of this research was to establish the scientific basis for the implementation of genomic selection in a composite Terminal sheep breeding scheme by providing consolidated linkage disequilibrium (LD) measures a ...
- DOI:
- 10.1186/s12863-017-0492-8
- PubMed:
- 28288558
- PubMed Central:
- PMC5348757
- https://doi.org/10.1186/s12863-017-0492-8
- Author:
- Flávio S. Schenkel, et al. ; Luiz Fernando Brito; John C. McEwan; Stephen Miller; Wendy Bain; Michael Lee; Ken Dodds; Sheryl-Anne Newman; Natalie Pickering; Shannon Clarke; Show all 10 Authors
- Source:
- Small ruminant research 2017 v.154 pp. 81-91
- ISSN:
- 0921-4488
- Subject:
- antagonism; breeding programs; carcass quality; carcass weight; data collection; economic valuation; genetic correlation; genetic improvement; genetic variation; heritability; ingestion; marbling; meat; pH; phenotype; selection index; sheep; sheep breeds; sires; ultrasonics; New Zealand
- Abstract:
- ... Meat quality and carcass characteristics are becoming more relevant for the sheep breeding programs because of their economic value. Understanding the genetic basis for these traits and its relationship with standard traits is necessary for this to be accomplished. Genetic and phenotypic parameters were estimated for 33 growth, carcass and meat quality traits using a large and unique data set from ...
- DOI:
- 10.1016/j.smallrumres.2017.07.011
- https://doi.org/10.1016/j.smallrumres.2017.07.011
- Author:
- Flávio S. Schenkel, et al. ; Lawrence R. Schaeffer; Paul J. Boettcher; Show all 3 Authors
- Source:
- Genetics, selection, evolution 2002 v.34 no.1 pp. 41
- ISSN:
- 0999-193X
- Subject:
- Bayesian theory; animal models; animals; bias; breeding value; correlation; estimation; evolution; heritability; information; parents; pedigree; phenotype; population; sampling; simulation models
- Abstract:
- ... Bayesian (via Gibbs sampling) and empirical BLUP (EBLUP) estimation of fixed effects and breeding values were compared by simulation. Combinations of two simulation models (with or without effect of contemporary group (CG)), three selection schemes (random, phenotypic and BLUP selection), two levels of heritability (0.20 and 0.50) and two levels of pedigree information (0% and 15% randomly missing ...
- DOI:
- 10.1186/1297-9686-34-1-41
- PubMed:
- 11929624
- PubMed Central:
- PMC2705422
- https://doi.org/10.1186/1297-9686-34-1-41
- Author:
- Flávio S Schenkel, et al. ; Yuri T. Utsunomiya; Adriana S. do Carmo; Roberto Carvalheiro; Haroldo HR Neves; Márcia C Matos; Ludmilla B Zavarez; Ana M Pérez O’Brien; Johann Sölkner; John C McEwan; John B Cole; Curtis P Van Tassell; Marcos VGB da Silva; Laercio R Porto Neto; Tad S Sonstegard; José F Garcia; Show all 16 Authors
- Source:
- BMC genetics 2013 v.14 no.52 pp. -
- ISSN:
- 1471-2156
- Subject:
- Nellore; beef cattle; birth weight; body conformation; body size; breeding value; bulls; calving; carcass weight; chromosome mapping; chromosomes; genes; humans; liveweight gain; mice; pregnancy; quantitative trait loci; single nucleotide polymorphism; swine; zebu; Brazil
- Abstract:
- ... Birth weight (BW) is an economically important trait in beef cattle, and is associated with growth- and stature-related traits and calving difficulty. One region of the cattle genome, located on Bos primigenius taurus chromosome 14 (BTA14), has been previously shown to be associated with stature by multiple independent studies, and contains orthologous genes affecting human height. A genome-wide a ...
- Handle:
- 10113/57013
- DOI:
- 10.1186/1471-2156-14-52
- PubMed:
- 23758625
- PubMed Central:
- PMC3683327
- https://doi.org/10.1186/1471-2156-14-52
- Author:
- Flávio S Schenkel, et al. ; Haroldo HR Neves; Roberto Carvalheiro; Ana M Pérez O’Brien; Yuri T Utsunomiya; Adriana S do Carmo; Johann Sölkner; John C McEwan; Curtis P Van Tassell; John B Cole; Marcos VGB da Silva; Sandra A Queiroz; Tad S Sonstegard; José Fernando Garcia; Show all 14 Authors
- Source:
- Genetics, selection, evolution 2014 v.46 no.1 pp. 2660
- ISSN:
- 0999-193X
- Subject:
- Nellore; beef; bulls; carcass weight; early development; finishing; genetic improvement; genetic merit; gestation period; marker-assisted selection; models; prediction; principal component analysis; regression analysis; scrotum; selection index; single nucleotide polymorphism; weaning; young animals; zebu
- Abstract:
- ... BACKGROUND: Nellore cattle play an important role in beef production in tropical systems and there is great interest in determining if genomic selection can contribute to accelerate genetic improvement of production and fertility in this breed. We present the first results of the implementation of genomic prediction in a Bos indicus (Nellore) population. METHODS: Influential bulls were genotyped w ...
- Handle:
- 10113/58866
- DOI:
- 10.1186/1297-9686-46-17
- PubMed:
- 24575732
- PubMed Central:
- PMC4014866
- https://doi.org/10.1186/1297-9686-46-17
- Author:
- Flávio S. Schenkel, et al. ; Yuri T. Utsunomiya; Adriana S. Carmo; Haroldo H. R. Neves; Roberto Carvalheiro; Márcia C. Matos; Ludmilla B. Zavarez; Pier K. R. K. Ito; Ana M. Pérez O'Brien; Johann Sölkner; Laercio R. Porto-Neto; John McEwan; John Cole B.; Marcos V. G. B. da Silva; Curtis P. Van Tassell; Tad S. Sonstegard; José Fernando Garcia; Show all 17 Authors
- Source:
- PloS one 2014 v.9 no.2 pp. 1-9
- ISSN:
- 1932-6203
- Subject:
- Nellore; animal models; beef; beef industry; body size; bulls; early development; genes; herds; linkage groups; loci; male fertility; molecular biology; phenotype; quantitative trait loci; reproductive performance; scrotum; single nucleotide polymorphism; variance; zebu
- Abstract:
- ... The reproductive performance of bulls has a high impact on the beef cattle industry. Scrotal circumference (SC) is the most recorded reproductive trait in beef herds, and is used as a major selection criterion to improve precocity and fertility. The characterization of genomic regions affecting SC can contribute to the identification of diagnostic markers for reproductive performance and uncover m ...
- Handle:
- 10113/58872
- DOI:
- 10.1371/journal.pone.0088561
- PubMed:
- 24558400
- PubMed Central:
- PMC3928245
- https://doi.org/10.1371/journal.pone.0088561