Jump to Main Content
- Franco, João J., et al. Show all 13 Authors
- International journal of biological macromolecules 2017 v.103 pp. 25-35
- Bothrops; Leishmania amazonensis; Trypanosoma cruzi; adenocarcinoma; amino acids; apoptosis; breasts; chromatography; cytotoxicity; databases; enzyme activity; epithelial cells; humans; hydrophobicity; proteins; snakes; venoms
- ... A new l-amino acid oxidase (LAAO) from Bothrops jararacussu venom (BjussuLAAO-II) was isolated by using a three-step chromatographic procedure based on molecular exclusion, hydrophobicity, and affinity. BjussuLAAO-II is an acidic enzyme with pI=3.9 and molecular mass=60.36kDa that represents 0.3% of the venom proteins and exhibits high enzymatic activity (4884.53U/mg/mim). We determined part of th ...