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- Galvão, Alexandre F. C., et al. Show all 10 Authors
- BMC complementary and alternative medicine 2016 v.16 no.1 pp. 199
- Apocynaceae; Byrsonima; Duranta erecta; Euphorbiaceae; Ipomoea; Ixora coccinea; Miconia; Momordica charantia; Moraceae; Ocotea; Pavonia; Psychotria; Sapindaceae; Schefflera morototoni; Solanum; Xylopia frutescens; Zanthoxylum rhoifolium; alternative medicine; biodiversity; chloroform; cytotoxicity; flora; flowers; fruits; hexane; leaves; medicinal plants; neoplasm cells; neoplasms; quercetin; solvents; stems; traditional medicine; Brazil
- ... BACKGROUND: Great biodiversity is a highlight of Brazilian flora. In contrast, the therapeutic potentialities of most species used in folk medicine remain unknown. Several of these species are commonly used to treat cancer. In this study, we investigated the cytotoxic activity of 18 plants from 16 families that are found in the northeast region of Brazil. METHODS: The following species were studie ...
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- Galvão, Alexandre F. C., et al. Show all 14 Authors
- Journal of natural products 2016 v.79 no.6 pp. 1524-1531
- Guatteria; alkaloids; bark; cytotoxicity; neoplasm cells; spectral analysis
- ... Phytochemical investigation of the bark of Guatteria friesiana afforded 12 new aporphines (1–12), along with nine known alkaloids (13–21). The structures of the new alkaloids were determined on the basis of spectroscopic data interpretation. The cytotoxic activity of the isolated compounds against a small panel of tumor cell lines was assessed using the Alamar blue assay. ...