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- Granado, Miriam, et al. Show all 8 Authors
- Nutrients 2019 v.11 no.1
- acetylcholine; adiponectin; anti-inflammatory activity; antioxidants; aorta; bioavailability; blood serum; brown adipose tissue; cysteine; cytokines; diabetes; energy intake; food intake; functional foods; garlic; gene expression regulation; gene overexpression; high density lipoprotein cholesterol; hypothalamus; inflammation; insulin; laboratory animals; leptin; leptin receptors; lipid metabolism; low density lipoprotein cholesterol; males; melanoidins; messenger RNA; neuropeptides; obesity; peroxisome proliferator-activated receptor gamma; potassium chloride; pro-opiomelanocortin; rats; sucrose; triacylglycerols; vasoconstriction
- ... Aged black garlic (ABG) is a functional food with antioxidant and anti-inflammatory properties. Recent studies also report its beneficial metabolic effects in a context of obesity or diabetes, although the mechanisms involved are poorly understood. The aim of this work was to analyze the effects of an ABG extract in the vascular and metabolic alterations induced by a high-fat/sucrose diet in rats. ...
- Granado, Miriam, et al. Show all 6 Authors
- Molecular and cellular endocrinology 2011 v.337 no.1-2 pp. 101-113
- adults; apoptosis; astrocytes; cerebellum; diabetic complications; ghrelin; glucose; homeostasis; hypothalamus; insulin; insulin-dependent diabetes mellitus; prolactin; rats; somatotropin; streptozotocin; tissues
- ... Poorly controlled type1 diabetes is associated with hormonal imbalances and increased cell death in different tissues, including the pituitary, hypothalamus and cerebellum. In the pituitary, lactotrophs are the cell population with the greatest increase in cell death, whereas in the hypothalamus and cerebellum astrocytes are most highly affected. Insulin treatment can delay, but does not prevent, ...