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- Gulyaeva, Lyudmila F., et al. Show all 5 Authors
- Molecular biology reports 2018 v.45 no.6 pp. 1937-1945
- DDT (pesticide); animal ovaries; endometrium; females; humans; insecticides; liver; mammary glands; mechanism of action; messenger RNA; microRNA; rats; receptors
- ... A non-genotoxic insecticide dichlorodiphenyltrichloroethane (DDT), can affect mRNA and microRNA levels, however, its precise mechanism of action remains poorly understood. Using in silico methods we found that the rat miR-190 family is potentially regulated by CAR and ER receptors activated by DDT. We showed that exposure to DDT results in a dose- and organ-dependent increase in the expression of ...