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- Hahn, Steve, et al. Show all 8 Authors
- Molecular cell 2017 v.68 no.1 pp. 130-143.e5
- DNA-directed RNA polymerase; RNA; acetyltransferases; genes; mutation; transcription (genetics); yeasts
- ... Prior studies suggested that SAGA and TFIID are alternative factors that promote RNA polymerase II transcription, with about 10% of genes in S. cerevisiae dependent on SAGA. We reassessed the role of SAGA by mapping its genome-wide location and role in global transcription in budding yeast. We find that SAGA maps to the UAS elements of most genes, overlapping with Mediator binding and irrespective ...
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