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- Hamid Zarkesh-Esfahani, Sayyed, et al. Show all 11 Authors
- Veterinary parasitology 2015 v.212 no.3-4 pp. 130-139
- DNA; Leishmania donovani; Leishmania infantum; antigens; cysteine proteinases; delayed hypersensitivity; dog diseases; dogs; electroporation; humans; immune response; immunoglobulin G; interferon-gamma; interleukin-10; nanoparticles; parasites; recombinant vaccines; tumor necrosis factor-alpha; vaccination; vaccine development; visceral leishmaniasis
- ... Visceral leishmaniasis (VL) is a fatal disease caused by the intracellular protozoan parasite Leishmania infantum. Dogs are the primary reservoirs of this parasite, and vaccination of dogs could be an effective method to reduce its transfer to humans. In order to develop a vaccine against VL (apart from the choice of immunogenic candidate antigens), it is necessary to use an appropriate delivery s ...