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- Han, Hae Jung, et al. Show all 7 Authors
- The journal of microbiology 2019 v.57 no.2 pp. 163-169
- antibodies; antigens; body temperature; body weight changes; dose response; ferrets; hemagglutinins; immunization; immunogenicity; influenza; intramuscular injection; mice; models; nasal cavity; seroconversion; signs and symptoms (animals and humans); vaccines; viral load; viruses
- ... To evaluate the efficacy of a non-adjuvant A/H1N1/2009 influenza A vaccine (GC1115), we demonstrated the immunogenicity and protective efficacy of GC1115 in mouse and ferret models. The immunogenicity of GC1115 was confirmed after intramuscular administration of 1.875, 3.75, 7.5, and 15 μg hemagglutinin antigen (HA) in mice and 7.5, 15, and 30 μg HA in ferrets at 3-week intervals. A single immuniz ...
- Han, Hae Jung, et al. Show all 15 Authors
- Vaccine 2019 v.37 no.3 pp. 484-493
- Influenza A virus; adjuvants; aluminum hydroxide; animal tissues; antibodies; antigens; blood serum; brain; clinical trials; cross reaction; ferrets; genes; hemagglutinins; human diseases; immunogenicity; kidneys; lungs; mice; models; neutralization tests; pandemic; spleen; vaccines; virus replication; viruses
- ... Because H5N1 influenza viruses continuously threaten the public health, the WHO has prepared various clades of H5N1 mock-up vaccines as one of the measures for pandemic preparedness. The recent worldwide outbreak of H5Nx virus which belongs to clade 220.127.116.11 and of which H5N6 subtype belongs and already caused human infection also increases the need of pandemic vaccine for such novel emerging virus ...
- Han, Hae Jung, et al. Show all 9 Authors
- BMC complementary and alternative medicine 2018 v.18 no.1 pp. 149
- alternative medicine; analgesic effect; antioxidant activity; antioxidants; anxiety; bioactive compounds; elevated plus-maze test; glutathione peroxidase; hippocampus; humans; hydrolysates; intravenous injection; liver function; males; menopause; nitric oxide synthase; oxidative stress; placenta; rats; staining; swimming
- ... BACKGROUND: Human placenta hydrolysate (hPH) has been utilized to improve menopausal, fatigue, liver function. Its high concentration of bioactive substances is known to produce including antioxidant, anti-inflammatory and anti-nociceptive activities. However, its mechanisms of stress-induced depression remain unknown. METHODS: The present study examined the effect of hPH on stress-induced depress ...
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