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- Harris-Johnson, Kelley S., et al. Show all 4 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2009 v.106 no.38 pp. 16287-16292
- epithelium; esophagus; foregut; mice; mutants; respiratory system; stomach
- ... The mammalian respiratory system, consisting of both trachea and lung, initiates from the foregut endoderm. The molecular program that instructs endodermal cells to adopt the respiratory fate is not fully understood. Here we show that conditional inactivation of β-Catenin (also termed Ctnnb1) in foregut endoderm leads to absence of both the trachea and lung due to a failure in maintaining the resp ...
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