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- Hicks, Kayla, et al. Show all 5 Authors
- Archives of biochemistry and biophysics 2019 v.662 pp. 143-150
- 3-hydroxybutyric acid; adults; anaerobic conditions; beta oxidation; calcium; carbon dioxide; dose response; energy; glucose; heart; hypoxia; ketone bodies; ketosis; myocytes; oxygen; rats; substrate specificity
- ... β-hydroxybutyrate is the primary ketone body produced by the body during ketosis and is used to meet its metabolic demands. The healthy adult heart derives most of its energy from fatty acid oxidation. However, in certain diseases, the heart alters its substrate preference and increases its ketone body metabolism. Little is known about the effects of βOHB on ventricular myocyte excitation-contract ...