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- Hochu, Gabrielle, et al. Show all 8 Authors
- Biomaterials 2016 v.96 pp. 1-10
- apoptosis; complementary DNA; cytokines; death domain receptors; endocytosis; ligands; models; nanocarriers; nanofibers; necrosis; neoplasm cells; neoplasms; phospholipase A2; plasma membrane
- ... Direct delivery of cytokines using nanocarriers holds great promise for cancer therapy. However, the nanometric scale of the vehicles made them susceptible to size-dependent endocytosis, reducing the plasma membrane-associated apoptosis signaling. Herein, we report a tumor microenvironment-responsive and transformable nanocarrier for cell membrane targeted delivery of cytokine. This formulation is ...