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- Holwerda, EvertK., et al. Show all 7 Authors
- Biotechnology for biofuels 2017 v.10 no.1 pp. 108
- Clostridium thermocellum; acetates; biofuels; bioprocessing; cellulose; ethanol; fermentation; gene targeting; hydrogen production; kinetics; knockout mutants; lactic acid; leucine; malates; metabolic engineering; metabolites; models; nitrogen; phenotype; prediction; pyruvic acid; valine
- ... BACKGROUND: Clostridium thermocellum is a Gram-positive anaerobe with the ability to hydrolyze and metabolize cellulose into biofuels such as ethanol, making it an attractive candidate for consolidated bioprocessing (CBP). At present, metabolic engineering in C. thermocellum is hindered due to the incomplete description of its metabolic repertoire and regulation within a predictive metabolic model ...
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