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- Housand, Conrad, et al. Show all 12 Authors
- Chemosphere 2014 v.94 pp. 91-96
- Bayesian theory; Markov chain; Monte Carlo method; bioaccumulation; blubber; data collection; mice; model uncertainty; models; pharmacokinetics; pollutants; polychlorinated biphenyls; prediction; probability distribution; rats; whales; wild animals; Tasmania
- ... Physiologically based pharmacokinetic (PBPK) models for wild animal populations such as marine mammals typically have a high degree of model uncertainty and variability due to the scarcity of information and the embryonic nature of this field. Parameters values used in marine mammals models are usually taken from other mammalian species (e.g. rats or mice) and might not be entirely suitable to pro ...