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- Houston, P.M., et al. Show all 10 Authors
- Proceedings of the National Academy of Sciences of the United States of America 1997 v.94 no.26 pp. 14924-14929
- mice; mutants; liver; mutagenesis; enzyme activity; starvation; glucocorticoids; corticosterone; blood chemistry; thymus gland; adrenal glands; weight; hormone secretion; hormonal regulation; blood glucose; body weight; obesity; hyperglycemia; glycogen; genetic recombination; high fat diet; gluconeogenesis
- ... Glucocorticoid hormones, acting via nuclear receptors, regulate many metabolic processes, including hepatic gluconeogenesis. It recently has been recognized that intracellular glucocorticoid concentrations are determined not only by plasma hormone levels, but also by intracellular 11 beta-hydroxysteroid dehydrogenases (11 beta-HSDs), which interconvert active corticosterone (cortisol in humans) an ...
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