PubAg

Main content area

You searched for: Author "Huang, Li-Yen Mae" Remove constraint Author: "Huang, Li-Yen Mae"
Start Over

Search

1  Search Results

1 entry found
Number of results to display per page

Search Results

1. Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons

Author:
Huang, Li-Yen Mae,   et al.   ; Chen, Yong; Zhang, Xiaofei; Wang, Congying; Li, GuangWen; Gu, Yanping;     Show all 6 Authors
Source:
Proceedings of the National Academy of Sciences of the United States of America 2008 v.105 no.43 pp. 16773-16778
ISSN:
0027-8424
Subject:
adenosine triphosphate; agonists; animal injuries; antagonists; cytotoxicity; ganglia; gene expression regulation; nociception; pain; rats; receptors; sensory neurons; small interfering RNA; spinal cord
Abstract:
... Purinergic ionotropic P2X7 receptors (P2X7Rs) are closely associated with excitotoxicity and nociception. Inhibition of P2X7R activation has been considered as a potentially useful strategy to improve recovery from spinal cord injury and reduce inflammatory damage to trauma. The physiological functions of P2X7Rs, however, are poorly understood, even though such information is essential for making ...
DOI:
10.1073/pnas.0801793105
PubMed:
18946042
PubMed Central:
PMC2575495