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- Huang, Li-Yen Mae, et al. Show all 6 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2008 v.105 no.43 pp. 16773-16778
- adenosine triphosphate; agonists; animal injuries; antagonists; cytotoxicity; ganglia; gene expression regulation; nociception; pain; rats; receptors; sensory neurons; small interfering RNA; spinal cord
- ... Purinergic ionotropic P2X7 receptors (P2X7Rs) are closely associated with excitotoxicity and nociception. Inhibition of P2X7R activation has been considered as a potentially useful strategy to improve recovery from spinal cord injury and reduce inflammatory damage to trauma. The physiological functions of P2X7Rs, however, are poorly understood, even though such information is essential for making ...
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