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- Huang, Shen-Da, et al. Show all 10 Authors
- International journal of biological macromolecules 2020 v.146 pp. 202-211
- AMP-activated protein kinase; Bacillus amyloliquefaciens; blood glucose; cell lines; epithelial cells; exopolysaccharides; galactose; glucagon-like peptide 1; glucose; glucose tolerance tests; glycemic control; glycemic effect; hepatocytes; high performance liquid chromatography; insulin receptor substrate proteins; intestinal mucosa; intraperitoneal injection; mannose; mice; phosphatidylinositol 3-kinase; polymers; probiotics; secretion; soil
- ... Bacillus amyloliquefaciens is a probiotic for animals. A strain of B. amyloliquefaciens designated amy-1 was isolated from soil, and the exopolysaccharides (EPSs) of the strain were characterized in terms of their effect on glycemic control. The EPSs were composed of mannose, glucose, and galactose, with the major components being polymers larger than 1000 kDa as revealed by size-exclusion high-pe ...
- Huang, Shen-Da, et al. Show all 8 Authors
- Journal of functional foods 2014 v.10 pp. 260-273
- AMP-activated protein kinase; Cucurbita moschata; animal disease models; ferulic acid; glycemic effect; insulin; insulin resistance; insulin-like effect; mice; noninsulin-dependent diabetes mellitus; pumpkins; screening
- ... Pumpkin has been suggested to have an antidiabetic effect, but the bioactives involved and molecular mechanisms mediating its hypoglycaemic activity are not clear. This study characterized some of the hypoglycaemic constituents in the crude extract of the Cucurbita moschata stem and investigated the mechanisms of their action. The C. moschata stem extract showed a hypoglycaemic effect in vivo in s ...