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- HuangX. Huang and W. Zhao contributed equally to this work., Xin, et al. Show all 7 Authors
- Chemical communications 2019 v.55 no.14 pp. 2070-2073
- Lewis acids; chemical communication; chloroform; deprotonation
- ... A three-component reaction between benzyne, oxazolines and chloroform was developed for the synthesis of trichloromethylated chiral oxazolidines. Benzyne not only serves as an electrophile towards oxazolines but also acts as a base for the deprotonation of chloroform. The dual functions of benzyne enable the trichloromethylation of chiral oxazolines and thus construct chiral N,O-quaternary stereoc ...