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- Jin, Fanxue, et al. Show all 7 Authors
- Journal of ethnopharmacology 2011 v.133 no.2 pp. 484-489
- agonists; cardiovascular diseases; disease prevention; endothelium; guanosine triphosphate; myosin light chains; phenylephrine; phosphorylation; protein kinase C; rats; sodium fluoride
- ... AIM OF THE STUDY: HMC05, an extract from eight different herbal mixtures, has been developed to treat cardiovascular disease. This extract has a vasorelaxant and anti-atherosclerotic action. We hypothesized that HMC05 attenuates vascular contraction through inhibition of the RhoA/Rho-kinase signaling pathway. MATERIALS AND METHODS: Rat aortic ring preparations were mounted in organ baths and subje ...