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- Author:
- Jong H. Kim, et al. ; Adedamola S. Arojojoye; Chibuzor Olelewe; Sean Parkin; Samuel G. Awuah; Show all 5 Authors
- Source:
- Chemical communications 2022 v.58 no.73 pp. 10237-10240
- ISSN:
- 1364-548X
- Subject:
- antineoplastic activity; catalytic activity; drug therapy; gold; materials science; medicine
- Abstract:
- ... Emerging synthetic development of chiral gold(iii) complexes has prompted new opportunities in catalysis and material science with limited utility in biomedicine. Here, we demonstrate potential chemotherapeutic capability of [C^N]Au(iii)Cl(R-DuPhos) (1–7) complexes, containing 1,2-bis[(2R,5R)-2,5-dialkylphospholano]benzene, which shows good stabilty, potent anticancer activity, and tolerability in ...
- DOI:
- 10.1039/d2cc03081k
- https://doi.org/10.1039/d2cc03081k
2. Design of a Flexible Thin-Film Encapsulant with Sandwich Structures of Perhydropolysilazane Layers
- Author:
- Jong H. Kim, et al. ; Dajeong Kim; Gyeong G. Jeon; Jincheol Kim; Nochang Park; Show all 5 Authors
- Source:
- ACS applied materials & interfaces 2022 v.14 no.30 pp. 34678-34685
- ISSN:
- 1944-8252
- Subject:
- ambient temperature; encapsulation; irradiation; relative humidity; silica; water vapor
- Abstract:
- ... Perovskite solar cells (PSCs) have attracted considerable attention due to their excellent photovoltaic properties, but stability issues have prevented their widespread application. PSCs must be protected by encapsulation to extend their lifetime. Here, we show that perhydropolysilazane (PHPS)-based multilayered encapsulation improves the lifetime of PSCs. The PSCs were encapsulated by converting ...
- DOI:
- 10.1021/acsami.2c06699
- https://doi.org/10.1021/acsami.2c06699
- Author:
- Jong H. Kim, et al. ; Byeong M. Oh; Yongcheol Jeong; Jian Zheng; Na Young Cho; Myungkwan Song; Jin Woo Choi; Show all 7 Authors
- Source:
- Chemical communications 2021 v.57 no.95 pp. 12824-12827
- ISSN:
- 1364-548X
- Subject:
- azides; irradiation; ligands; synthesis; ultraviolet radiation
- Abstract:
- ... In this study, we report a UV-light-curable azide ligand (AzL) for the micro-patterning of PeQDs. AzL can be attached to the surface of the PeQDs during their synthesis without additional ligand exchange. Using the AzL-grafted CsPbBr₃ PeQDs, high-color-purity 240 × 240 μm² square-shaped patterns were successfully fabricated using UV light irradiation, which corresponds to a resolution of >50 pixel ...
- DOI:
- 10.1039/d1cc05892d
- https://doi.org/10.1039/d1cc05892d
- Author:
- Jong H. Kim, et al. ; Hyeong Ju Eun; Hyojin Kye; Dahee Kim; In Su Jin; Jae Woong Jung; Seo-Jin Ko; Junseok Heo; Bong-Gi Kim; Show all 9 Authors
- Source:
- ACS applied materials & interfaces 2021 v.13 no.9 pp. 11144-11150
- ISSN:
- 1944-8252
- Subject:
- absorption; ambient temperature; lighting; polymers
- Abstract:
- ... Near-infrared organic photodetectors (NIR OPDs) have attracted considerable attention because of their inherent advantages such as a tailorable light absorption property, low-cost fabrication, compatibility with flexible substrates, and room-temperature operation. In particular, the development of NIR detection between 900 and 950 nm is crucial for noise-free communication in ambient environments. ...
- DOI:
- 10.1021/acsami.0c22808
- https://doi.org/10.1021/acsami.0c22808
- Author:
- Jong H Kim, et al. ; Kathleen L Chan; Noreen Mahoney; Luisa W Cheng; Nicole Tautges; Kate Scow; Show all 6 Authors
- Source:
- Journal of the science of food and agriculture 2020 v.100 no.6 pp. 2800-2806
- ISSN:
- 0022-5142
- Subject:
- Aspergillus flavus; adverse effects; aflatoxins; antifungal agents; antifungal properties; apples; bioassays; carcinogenicity; corn; food contamination; food matrix; food processing; fungal contamination; fungi; fungicides; grape juice; human health; organic foods; pH; pathogens; sanitation; soil; soil pollution; soil sampling; thiabendazole; tomatoes
- Abstract:
- ... BACKGROUND: Contamination of food or the environment by fungi, especially those resistant to conventional fungicides or drugs, represents a hazard to human health. The objective of this study is to identify safe, natural antifungal agents that can remove fungal pathogens or contaminants rapidly from food and / or environmental sources. RESULTS: Fifteen antifungal compounds (nine benzo derivatives ...
- DOI:
- 10.1002/jsfa.10288
- https://doi.org/10.1002/jsfa.10288
- Author:
- Jong H. Kim, et al. ; Kathleen L. Chan; Christina C. Tam; Luisa W. Cheng; Kirkwood M. Land; Fatih Yildiz; Show all 6 Authors
- Source:
- Cogent food & agriculture 2020 v.6 no.1 pp. 1823593
- ISSN:
- 2331-1932
- Subject:
- Saccharomyces cerevisiae; agriculture; antioxidants; cell walls; chloroquine; toxicity; yeasts
- Abstract:
- ... We would like to comment on a recent study where the redox-modulatory anti-protozoal drug chloroquine has shown to trigger a crosstalk between the antioxidant and cell wall integrity systems in the yeast Saccharomyces cerevisiae. This note discusses the redox-active potential of the natural compound 2-hydroxy-4-methoxybenzaldehyde (2H4M) which could also serve as a potent redox-cycler in fungal (y ...
- DOI:
- 10.1080/23311932.2020.1823593
- CHORUS:
- 10.1080/23311932.2020.1823593
- https://doi.org/10.1080/23311932.2020.1823593
- Author:
- Jong H. Kim, et al. ; Christina C. Tam; Kevin Nguyen; Daniel Nguyen; Sabrina Hamada; Okhun Kwon; Irene Kuang; Steven Gong; Sydney Escobar; Max Liu; Jihwan Kim; Tiffany Hou; Justin Tam; Luisa W. Cheng; Kirkwood M. Land; Mendel Friedman; Show all 16 Authors
- Source:
- BMC complementary medicine and therapies 2021 v.21 no.1 pp. 229
- ISSN:
- 2662-7671
- Subject:
- Bacillus cereus; Candida albicans; Lactobacillus; Salmonella enterica; Solanum pimpinellifolium; Trichomonas vaginalis; Tritrichomonas foetus; antibacterial properties; antifungal properties; antiprotozoal properties; caffeic acid; chemical composition; chlorogenic acid; color; fruit peels; fruits; glycoalkaloids; leaves; powders; quercetin; stems; tomatoes; vagina; wild relatives
- Abstract:
- ... BACKGROUND: We previously reported that the tomato glycoalkaloid tomatine inhibited the growth of Trichomonas vaginalis strain G3, Tritrichomonas foetus strain D1, and Tritrichomonas foetus-like strain C1 that cause disease in humans and farm and domesticated animals. The increasing prevalence of antibiotic resistance requires development of new tools to enhance or replace medicinal antibiotics. M ...
- Handle:
- 10113/7504415
- DOI:
- 10.1186/s12906-021-03391-2
- https://doi.org/10.1186/s12906-021-03391-2
- Author:
- Jong H Kim, et al. ; Min G Park; Woo J Kim; Jae Y Choi; Dong H Park; Jun Y Kim; Minghui Wang; Yeon H Je; Show all 8 Authors
- Source:
- Pest management science 2020 v.76 no.5 pp. 1699-1704
- ISSN:
- 1526-498X
- Subject:
- Apis cerana; Bacillus thuringiensis; RNA interference; Sacbrood virus; autolysis; bee viruses; cost effectiveness; double-stranded RNA; entomopathogenic bacteria; genes; pest management; transcription (genetics); viruses; worker honey bees; South Korea
- Abstract:
- ... BACKGROUND: Sacbrood virus (SBV) is a fatal viruses that infects the Asian honey bee, Apis cerana in Korea. Recently, RNA interference (RNAi) has been suggested as a promising strategy for the suppression of honey bee viruses. For the efficient control of SBV infection using RNAi, simple and cost‐effective methods to produce double‐stranded RNA (dsRNA) are needed. RESULTS: To develop a dsRNA produ ...
- DOI:
- 10.1002/ps.5692
- https://doi.org/10.1002/ps.5692
- Author:
- Jong H. Kim, et al. ; Mendel Friedman; Christina C. Tam; Sydney Escobar; Steven Gong; Max Liu; Xuan Yu Mao; Cindy Do; Irene Kuang; Kelvin Boateng; Janica Ha; Megan Tran; Srimanth Alluri; Tam Le; Ryan Leong; Luisa W. Cheng; Kirkwood M. Land; Show all 17 Authors
- Source:
- Foods 2021 v.10 no.2 pp. -
- ISSN:
- 2304-8158
- Subject:
- Lactobacillus; Solanum lycopersicum var. cerasiforme; Trichomonas vaginalis; Tritrichomonas foetus; antiparasitic properties; assays; cats; cattle; cherry tomatoes; diarrhea; digestive tract; farms; freeze drying; functional foods; humans; infection; metronidazole; parasites; pomace; sexually transmitted diseases; trichomoniasis
- Abstract:
- ... Trichomoniasis in humans, caused by the protozoal parasite Trichomonas vaginalis, is the most common non-viral sexually transmitted disease, while Tritrichomonas foetus causes trichomonosis, an infection of the gastrointestinal tract and diarrhea in farm animals and domesticated cats. As part of an effort to determine the inhibitory effects of plant-based extracts and pure compounds, seven commerc ...
- DOI:
- 10.3390/foods10020230
- https://doi.org/10.3390/foods10020230
- Author:
- Jong H. Kim, et al. ; Kathleen L. Chan; Luisa W. Cheng; Lisa Tell; Barbara Byrne; Kristin Clothier; Kirkwood Land; Show all 7 Authors
- Source:
- Methods and protocols 2019 v.2 no.31 pp. -
- ISSN:
- 2409-9279
- Subject:
- Aspergillus fumigatus; active ingredients; animal pathogenic fungi; antifungal agents; antifungal properties; antioxidants; benzaldehyde; chemosensitization; cresols; drug design; drug resistance; extra-label drug use; fludioxonil; fungicide resistance; mutants; mycoses; thymol
- Abstract:
- ... Current antifungal interventions have often limited efficiency in treating fungal pathogens, particularly those resistant to commercial drugs or fungicides. Antifungal drug repurposing is an alternative intervention strategy, whereby new utility of various marketed, non-antifungal drugs could be repositioned as novel antifungal agents. In this study, we investigated “chemosensitization” as a metho ...
- Handle:
- 10113/6477322
- DOI:
- 10.3390/mps2020031
- PubMed:
- 31164611
- PubMed Central:
- PMC6632159
- https://doi.org/10.3390/mps2020031
- Author:
- Jong H. Kim, et al. ; Kathleeen L. Chan; Luisa W. Cheng; Show all 3 Authors
- Source:
- Molecules 2017 v.22 no.10 pp. 1-14
- ISSN:
- 1420-3049
- Subject:
- Aspergillus fumigatus; Saccharomyces cerevisiae; antioxidants; biopesticides; caspofungin; catalysts; cell walls; chemosensitization; cinnamic acid; cytotoxicity; drugs; fludioxonil; fungi; glutathione-disulfide reductase; minimum inhibitory concentration; mitogen-activated protein kinase; mitogen-activated protein kinase kinase; moieties; mutants; pathogens; structure-activity relationships
- Abstract:
- ... Disruption of fungal cell wall should be an effective intervention strategy. However, the cell wall-disrupting echinocandin drugs, such as caspofungin (CAS), cannot exterminate filamentous fungal pathogens during treatment. For potency improvement of cell wall-disrupting agents (CAS, octyl gallate (OG)), antifungal efficacy of thirty-three cinnamic acid derivatives was investigated against Sacchar ...
- Handle:
- 10113/5865661
- DOI:
- 10.3390/molecules22101783
- PubMed:
- 29065462
- PubMed Central:
- PMC6151797
- https://doi.org/10.3390/molecules22101783
- Author:
- Jong H. Kim, et al. ; Jongsung Park; Hyesun Yoo; Vijay Karade; Kuldeep Singh Gour; Eunyoung Choi; Moonyong Kim; Xiaojing Hao; So Jeong Shin; JunHo Kim; Hongjae Shim; Dongmyung Kim; Jaesung Yun; Jin hyeok Kim; Show all 14 Authors
- Source:
- Journal of materials chemistry A 2020 v.8 no.29 pp. 14538-14544
- ISSN:
- 2050-7496
- Subject:
- chemistry; copper zinc tin sulfide; electric potential difference; films (materials); halogens; lamps; light intensity; microscopy; selenides; solar cells; spectroscopy
- Abstract:
- ... In this study, we prepared three kesterite thin-film solar cells, Cu₂ZnSnSe₄ (CZTSe), Cu₂ZnSn(S,Se)₄ (CZTSSe), and Cu₂ZnSnS₄ (CZTS), and based on low light intensity measurements, examined the possibility of using kesterite devices for indoor applications. Interestingly, all the prepared cells exhibited nearly the same device efficiency under standard test conditions of 1 sun; however, under illum ...
- DOI:
- 10.1039/d0ta04863a
- https://doi.org/10.1039/d0ta04863a
- Author:
- Jong H. Kim, et al. ; Kathleen L. Chan; Noreen Mahoney; Show all 3 Authors
- Source:
- International journal of molecular sciences 2015 v.16 no.11 pp. 26850-26870
- ISSN:
- 1422-0067
- Subject:
- Aspergillus fumigatus; Penicillium; Saccharomyces cerevisiae; antifungal properties; benzaldehyde; carvacrol; cell walls; chemosensitization; fludioxonil; mitogen-activated protein kinase; mitogen-activated protein kinase kinase; mutants; pathogens; structure-activity relationships; thymol; yeasts
- Abstract:
- ... Disruption of cell wall integrity system should be an effective strategy for control of fungal pathogens. To augment the cell wall disruption efficacy of monoterpenoid phenols (carvacrol, thymol), antimycotic potency of benzaldehyde derivatives that can serve as chemosensitizing agents were evaluated against strains of Saccharomyces cerevisiae wild type (WT), slt2∆ and bck1∆ (mutants of the mitoge ...
- Handle:
- 10113/61675
- DOI:
- 10.3390/ijms161125988
- PubMed:
- 26569223
- PubMed Central:
- PMC4661847
- https://doi.org/10.3390/ijms161125988
- Author:
- Jong H. Kim, et al. ; Gyeong G. Jeon; Myeongjae Lee; Jinwoo Nam; Wongi Park; Minyong Yang; Jong-Ho Choi; Dong Ki Yoon; Eunji Lee; BongSoo Kim; Show all 10 Authors
- Source:
- ACS applied materials & interfaces 2018 v.10 no.35 pp. 29824-29830
- ISSN:
- 1944-8252
- Subject:
- ambient temperature; annealing; electrical properties; electrodes; nanowires; polymers; solvents; transistors
- Abstract:
- ... Electron donor (D)–acceptor (A)-type conjugated polymers (CPs) have emerged as promising semiconductor candidates for organic field-effect transistors. Despite their high charge carrier mobilities, optimization of electrical properties of D–A-type CPs generally suffers from complicated post-deposition treatments such as high-temperature thermal annealing or solvent-vapor annealing. In this work, w ...
- DOI:
- 10.1021/acsami.8b07643
- https://doi.org/10.1021/acsami.8b07643
- Author:
- Jong H. Kim, et al. ; Seung-Heon Lee; Byeong M. Oh; Chan Yoo Hong; Su-Kyo Jung; Sung-Ha Park; Gyeong G. Jeon; Young-Wan Kwon; Seokhoon Jang; Youngu Lee; Dongwook Kim; O-Pil Kwon; Show all 12 Authors
- Source:
- ACS applied materials & interfaces 2019 v.11 no.39 pp. 35904-35913
- ISSN:
- 1944-8252
- Subject:
- Lewis bases; anions; electron paramagnetic resonance spectroscopy; gases; naphthalene; transistors
- Abstract:
- ... The formation of stabilized radical anions on organic materials in the solid state is an important issue in radical-based fundamental research and various applications. Herein, for the first time, we report on gas-induced ion-free stable radical anion formation (SRAF) of organic semiconducting solids with high gas selectivities through the use of organic field-effect transistor (OFET) gas sensors ...
- DOI:
- 10.1021/acsami.9b12222
- https://doi.org/10.1021/acsami.9b12222
- Author:
- Jong H. Kim, et al. ; Sang Eun Yoon; Yeongkwon Kang; So Yeon Noh; Jeongwoo Park; Sang Yeon Lee; Jaehong Park; Dae Woon Lee; Dong Ryeol Whang; Taekyeong Kim; Gun-Ho Kim; Hyungtak Seo; Bong-Gi Kim; Show all 13 Authors
- Source:
- ACS applied materials & interfaces 2019 v.12 no.1 pp. 1151-1158
- ISSN:
- 1944-8252
- Subject:
- crystal structure; electrical conductivity; films (materials); polymers; semiconductors; temperature
- Abstract:
- ... Intercorrelation of thermoelectric properties of a doped conjugated semiconducting polymer (PIDF-BT) with charge carrier density, conductive morphology, and crystallinity are systematically investigated. Upon being doped with F4-TCNQ by the sequential doping method, PIDF-BT exhibited a high electrical conductivity over 210 S cm–¹. The significant enhancement of electrical conductivity resulted fro ...
- DOI:
- 10.1021/acsami.9b17825
- https://doi.org/10.1021/acsami.9b17825
- Author:
- Jong H. Kim, et al. ; Kathleen L. Chan; Show all 2 Author
- Source:
- Molecules 2014 v.19 no.11 pp. 18448-18464
- ISSN:
- 1420-3049
- Subject:
- Penicillium expansum; Penicillium italicum; antifungal agents; antifungal properties; chemosensitization; disease control; heat; hydrogen peroxide; in vitro studies; kojic acid; minimum inhibitory concentration; mutants; oxidants; oxidation; plant pathogenic fungi; temperature; toxicity
- Abstract:
- ... Oxidative treatment is one of the strategies for preventing Penicillium contamination in crops/foods. The antifungal efficacy of hydrogen peroxide (H2O2; oxidant) was investigated in Penicillium strains by using kojic acid (KA) as a chemosensitizing agent, which can enhance the susceptibility of pathogens to antifungal agents. Co-application of KA with H2O2 (chemosensitization) resulted in the enh ...
- Handle:
- 10113/60059
- DOI:
- 10.3390/molecules191118448
- PubMed:
- 25397736
- https://doi.org/10.3390/molecules191118448
- Author:
- Jong H. Kim, et al. ; William Hart-Cooper; Kathleen L. Chan; Luisa W. Cheng; William J. Orts; Kaj Johnson; Show all 6 Authors
- Source:
- Microbiology Discovery 2016 v.4 no.2 pp. -
- ISSN:
- 2052-6180
- Subject:
- Aspergillus; GRAS substances; antifungal agents; antifungal properties; antioxidants; benzaldehyde; bioassays; carvacrol; drugs; fludioxonil; fungicide resistance; microbial growth; models; mutants; preservatives; standard operating procedures; surfactants; synergism; thymol; vacuoles; yeasts
- Abstract:
- ... Background: Control of fungi is problematic, since effective methods for intervening fungal infection or contamination, especially for those resistant to drugs/fungicides, are often very limited. Generally regarded as safe (GRAS) agents, such as natural compounds or their structural analogs could be potential sources of sustainable antifungal agents. As a proof of concept, antifungal efficacy of t ...
- Handle:
- 10113/5678137
- DOI:
- 10.7243/2052-6180-4-2
- https://doi.org/10.7243/2052-6180-4-2
- Author:
- Jong H. Kim, et al. ; Noreen Mahoney; Kathleen L. Chan; Bruce C. Campbell; Ronald P. Haff; Larry H. Stanker; Show all 6 Authors
- Source:
- Frontiers in microbiology 2014 v.5 pp. 1-12
- ISSN:
- 1664-302X
- Subject:
- Aspergillus flavus; Aspergillus fumigatus; Aspergillus parasiticus; Saccharomyces cerevisiae; adverse effects; antifungal agents; antifungal properties; bioassays; cell walls; fungi; fungicides; heat stress; kojic acid; microbial growth; minimum inhibitory concentration; mitogen-activated protein kinase; mutants; nontoxigenic strains; pathogens; synergism
- Abstract:
- ... The aim of this study was to examine two benzo analogs, octylgallate (OG) and veratraldehyde (VT), as antifungal agents against strains of Aspergillus parasiticus and A.flavus (toxigenic or atoxigenic). Both toxigenic and atoxigenic strains used were capable of producing kojic acid, another cellular secondary product. A. fumigatus was used as a genetic model for this study. When applied independen ...
- Handle:
- 10113/58725
- DOI:
- 10.3389/fmicb.2014.00087
- PubMed:
- 24639673
- PubMed Central:
- PMC3945611
- https://doi.org/10.3389/fmicb.2014.00087
- Author:
- Jong H. Kim, et al. ; Bruce C. Campbell; Kathleen L. Chan; Noreen Mahoney; Ronald P. Haff; Show all 5 Authors
- Source:
- Molecules 2013 v.18 no.2 pp. 1564-1581
- ISSN:
- 1420-3049
- Subject:
- Penicillium griseofulvum; Aspergillus parasiticus; kojic acid; minimum inhibitory concentration; hosts; antifungal agents; hydrogen peroxide; yeasts; cell respiration; animal pathogenic fungi; mitochondria; plant pathogenic fungi; synergism; metabolic inhibitors; electron transport chain; Aspergillus flavus; antifungal properties
- Abstract:
- ... Co-application of certain types of compounds to conventional antimicrobial drugs can enhance the efficacy of the drugs through a process termed chemosensitization. We show that kojic acid (KA), a natural pyrone, is a potent chemosensitizing agent of complex III inhibitors disrupting the mitochondrial respiratory chain in fungi. Addition of KA greatly lowered the minimum inhibitory concentrations o ...
- Handle:
- 10113/56305
- DOI:
- 10.3390/molecules18021564
- PubMed:
- 23353126
- PubMed Central:
- PMC6269749
- https://doi.org/10.3390/molecules18021564