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- Kassem, Ali, et al. Show all 3 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2014 v.111 no.24 pp. 8943-8948
- RNA; Trypanosoma brucei; genes; glycoproteins; hosts; immune response; telomeres; transcription (genetics)
- ... African trypanosomes survive the immune defense of their hosts by regularly changing their antigenic coat made of variant surface glycoprotein (VSG). The Trypanosoma brucei genome contains more than 1,000 VSG genes. To be expressed, a given VSG gene must be located in one of 15 telomeric regions termed “VSG expression sites” (ESs), each of which contains a polycistronic transcription unit that inc ...
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