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1. The Drosophila jumonji gene encodes a JmjC-containing nuclear protein that is required for metamorphosis

Author:
Kato, Yasuko,   et al.   ; Sasai, Nobuhiro; Kimura, Gaku; Takeuchi, Takashi; Yamaguchi, Masamitsu;     Show all 5 Authors
Source:
FEBS journal 2007 v.274 no.23 pp. 6139-6151
ISSN:
1742-464X
Subject:
DNA-directed RNA polymerase; Drosophila; antibodies; cell proliferation; ecdysone; gene expression; genes; heterochromatin; larvae; metamorphosis; mice; mutants; mutation; phenotype; polytene chromosomes; repressor proteins; salivary glands; tissues; transcription (genetics); transgenic animals
Abstract:
... Jumonji (Jmj) is a transcriptional repressor that plays important roles in the suppression of cell proliferation and development of various tissues in the mouse. To further clarify the roles of Jmj during development and gain insight into mechanisms of Jmj-mediated transcriptional regulation, we have taken advantage of Drosophila as a model organism. Drosophila Jmj (dJmj) shares high homology with ...
DOI:
10.1111/j.1742-4658.2007.06135.x