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- Kikuchi, Kota, et al. Show all 15 Authors
- Biochemical and biophysical research communications 2019 v.512 no.4 pp. 653-658
- Alzheimer disease; amino acids; amyloid; blood serum; brain; fibroblasts; iron; patients
- ... Alzheimer's disease (AD) is characterized by the formation of extracellular amyloid plaques containing the amyloid β-protein (Aβ) within the parenchyma of the brain. Aβ42, which is 42 amino acids in length, is considered to be the key pathogenic factor in AD. Iron deposition is found abundantly in the amyloid plaques of AD patients; however, whether iron intake exacerbates amyloid deposition in vi ...