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- Kim, Cathy S., et al. Show all 5 Authors
- Journal of bacteriology 2011 v.193 no.24 pp. 6824-6833
- Mycobacterium smegmatis; antimicrobial peptides; bacteria; bacteriology; gene overexpression; genes; lysosomes; macrophages; mutants; mutation; oxidative stress; reactive oxygen species; resistance mechanisms; stress response; transcription factors; transposons
- ... The mycobactericidal properties of macrophages include the generation of reactive oxygen intermediates and the delivery of bacteria to a hydrolytic lysosome enriched in bactericidal ubiquitin-derived peptides (Ub-peptides). To better understand the interactions of ubiquitin-derived peptides with mycobacteria and identify putative mycobacterial intrinsic resistance mechanisms, we screened for trans ...
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