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- Koepsell, Hermann, et al. Show all 5 Authors
- Journal of Proteome Research 2015 v.14 no.1 pp. 353-365
- H+/K+-exchanging ATPase; H-transporting ATP synthase; absorption; antibodies; beta oxidation; carbohydrates; drugs; electron transport chain; fat intake; fatty acids; gene expression regulation; glucose transporters; glycolysis; glycosylation; high fat diet; immune response; immunosuppression; intestinal mucosa; major histocompatibility complex; mice; pentose phosphate cycle; pharmacokinetics; physiological transport; plasma membrane; protein content; proteome; proteomics; small intestine; sodium-potassium-exchanging ATPase; steroid metabolism; symporters
- ... Improved procedures for sample preparation and proteomic data analysis allowed us to identify 7700 different proteins in mouse small intestinal mucosa and calculate the concentrations of >5000 proteins. We compared protein concentrations of small intestinal mucosa from mice that were fed for two months with normal diet (ND) containing 34.4% carbohydrates, 19.6% protein, and 3.3% fat or high-fat di ...
- Koepsell, Hermann, et al. Show all 11 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.30 pp. E4111
- animal models; glucose; glucose transporters; image analysis; neoplasm cells; patients; positron-emission tomography; prostatic neoplasms; viability
- ... Cancers require high amounts of glucose to grow and survive, and dogma is that uptake is facilitated by passive glucose transporters (GLUTs). We have identified a new mechanism to import glucose into pancreatic and prostate cancer cells, namely active glucose transport mediated by sodium-dependent glucose transporters (SGLTs). This means that the specific radioactive imaging probe for SGLTs, α-met ...
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