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- Lee, Sung Ryul, et al. Show all 8 Authors
- Journal of ethnopharmacology 2020 v.258 pp. 112874
- Oriental traditional medicine; Salvia miltiorrhiza; animal models; blood circulation; bone density; bone resorption; estrogens; ethanol; gene expression; liver; liver diseases; menopause; mice; micro-computed tomography; osteocalcin; osteoclasts; osteoporosis; ovariectomy; plant extracts
- ... Salvia miltiorrhiza is a traditional oriental medicine widely used for preventing and treating disorders of the liver, menstrual, and blood circulation systems. Osteoporosis, loss of bone with age and/or estrogen deficiency, is an important causal factor of fracture. S. miltiorrhiza extract has been used to alleviate dysmenorrhea and painful osteoarthritis.This study was performed to investigate t ...
- Lee, Sung Ryul, et al. Show all 9 Authors
- Pharmaceutical biology 2018 v.56 no.1 pp. 32-42
- Arctium lappa; Cynanchum wilfordii; Dioscorea oppositifolia; aorta; diet; drugs; ethanol; fructose; inflammation; liver; liver function; mice; obesity; protein synthesis; root extracts; synergism; vascular cell adhesion molecules
- ... Context: Cynanchum wilfordii (Maximowicz) Hemsley (Apocynaceae), Arctium lappa L. var. rubescens Frivald (Asteraceae) and Dioscorea opposite Thunb (Dioscoreaceae) root extracts have been widely used as an alternative for intervening obesity. Objectives: The synergistic effect of three-herb mixture of C. wilfordii, A. lappa and D. opposita was determined on aortic and liver inflammatory responses. ...
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- Lee, Sung Ryul, et al. Show all 10 Authors
- Journal of agricultural and food chemistry 2016 v.64 no.18 pp. 3564-3573
- Arctium lappa; acetates; active ingredients; anaphylaxis; ethanol; histamine; interleukin-4; mice; mitogen-activated protein kinase; rats; roots; secretion; tumor necrosis factor-alpha
- ... The antiallergic potential of Arctium lappa L. was investigated in Sprague–Dawley rats, ICR mice, and RBL-2H3 cells. Ethanol extract (90%) of A. lappa (ALE, 100 μg/mL) inhibited the degranulation rate by 52.9%, determined by the level of β-hexosaminidase. ALE suppressed passive cutaneous anaphylaxis (PCA) in rats and attenuated anaphylaxis and histamine release in mice. To identify the active comp ...