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- Lee, Tina, et al. Show all 3 Authors
- Journal of organic chemistry 2012 v.77 no.8 pp. 4097-4102
- chemical reactions; chemical structure; organic chemistry; organic compounds; regioselectivity; salts
- ... The regioselective reduction of 3-substituted N-acylpyrazinium salts with n-Bu₃SnH has been developed for the synthesis of 3-substituted 1,2-dihydropyrazines in yields of 56–94%. Substitution of the pyrazinium salts with electron-donating groups favors the formation of the 1,2-isomers as a result of their better stability over the 1,6-isomers. Under mild acidic conditions, 3-methoxy substituted 1, ...