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- Lee, Yen Jea, et al. Show all 3 Authors
- Tetrahedron letters 2018
- Lewis bases; N-substituted glycines; azides; biomimetics; chemical bonding; chemical reactions; cyanides; moieties; triazoles
- ... The late-stage functionalization of a biomimetic foldamer such as a peptoid is a useful tool to achieve structural diversity. Herein, a facile method for the synthesis of triazole- or tetrazole-containing peptoids using post-synthetic modifications has been reported. On a resin-bound peptoid with a chloroalkyl side chain(s), substitution with nucleophiles (azide or cyanide) and the subsequent [3 + ...