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- Li, Yingxiu, et al. Show all 8 Authors
- Biochemical and biophysical research communications 2013 v.434 pp. 820-828
- epigenetics; lysine; histones; methylation; gene activation; bioinformatics; eukaryotic cells; DNA microarrays; gene expression; gene silencing; genes; heterochromatin; Drosophila
- ... Heterochromatin protein 1 (HP1) is an epigenetic gene silencing protein that is regulated by lysine 9 methylation of histone H3. Most eukaryotes have at least three HP1 homologs with similar domain structures but with different localization patterns and functions in heterochromatin and euchromatin. However, little is known about the genome-wide effects of the three main HP1 homologs on gene expres ...