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- Lin, Qing-yan, et al. Show all 2 Author
- Biotechnology letters 2020 v.42 no.1 pp. 35-44
- data collection; genes; genomics; hypoxia; lung neoplasms; neoplasm cells; patients
- ... OBJECTIVE: The study is to research how miR-34-SIRT1 is regulated during hypoxia in lung cancer cells. RESULTS: Analysis of publicly available datasets from patients with NSCLC did not reveal significant genomic alterations in RBM38, SIRT1, HIF1A, MIR34A, MIR34B, and MIR34C, but expectedly revealed alterations in TP53. Overall survival in NSCLC patients with or without alterations in these genes w ...