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- Liu, Naiquan, et al. Show all 8 Authors
- Biochemical and biophysical research communications 2017
- animal models; blood pressure; correlation; diabetes; digestive system; fibrosis; high fat diet; humans; hyperglycemia; inflammation; interleukin-1; intestinal microorganisms; kidney diseases; kidneys; low fat diet; males; metabolites; mice; obesity; oxidative stress; patients; phosphorylation; risk factors; trimethylamine; tumor necrosis factor-alpha
- ... Emerging evidence shows that obesity induces renal injury and is an independent risk factor for the development of chronic kidney disease (CKD), even without diabetes or hyperglycemia. Although multiple metabolic factors have been suggested to account for obesity-associated renal injury, the precious underlying mechanisms are not completely understood. Recent study shows that increased trimethylam ...