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- Liu, Wumei, et al. Show all 9 Authors
- Virus genes 2016 v.52 no.3 pp. 354-364
- Porcine epidemic diarrhea virus; Salmonella Typhimurium; Transmissible gastroenteritis virus; diarrhea; edible vaccines; financial economics; genes; humoral immunity; immune response; immunoglobulin G; interferon-gamma; interleukin-4; lymphocyte proliferation; neonates; neutralization; neutralizing antibodies; oral vaccination; piglets; recombinant vaccines; structural proteins; viruses
- ... Porcine transmissible gastroenteritis virus (TGEV) and porcine epidemic diarrhea virus (PEDV) can cause severe diarrhea in newborn piglets and led to significant economic losses. The S proteins are the main structural proteins of PEDV and TGEV capable of inducing neutralizing antibodies in vivo. In this study, a DNA vaccine SL7207 (pVAXD-PS1-TS) co-expressing S proteins of TGEV and PEDV delivered ...