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- Lopdell, T., et al. Show all 9 Authors
- Journal of dairy science 2019 v.102 no.4 pp. 3254-3258
- Hereford; X chromosome; bulls; cows; genetic analysis; genome; genome assembly; genome-wide association study; genotype; marker-assisted selection; single nucleotide polymorphism; statistical models
- ... In cattle, the X chromosome accounts for approximately 3 and 6% of the genome in bulls and cows, respectively. In spite of the large size of this chromosome, very few studies report analysis of the X chromosome in genome-wide association studies and genomic selection. This lack of genetic interrogation is likely due to the complexities of undertaking these studies given the hemizygous state of som ...
- Lopdell, T., et al. Show all 11 Authors
- Journal of dairy science 2017 v.100 no.7 pp. 5491-5500
- X chromosome; adults; bulls; calves; cattle breeding; dairy cattle; daughters; females; genes; genotype; inheritance (genetics); lactation; mammary glands; marker-assisted selection; mice; prediction; sequence analysis; stem cells; tissues; transcription (genetics)
- ... X chromosome inactivation (XCI) is a process by which 1 of the 2 copies of the X chromosomes present in female mammals is inactivated. The transcriptional silencing of one X chromosome achieves dosage compensation between XX females and XY males and ensures equal expression of X-linked genes in both sexes. Although all mammals use this form of dosage compensation, the complex mechanisms that regul ...