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1. Pulse‐based snacks as functional foods: Processing challenges and biological potential

Author:
Luis Mojica,   et al.   ; Alejandro Escobedo;     Show all 2 Author
Source:
Comprehensive reviews in food science and food safety 2021 v.20 no.5 pp. 4678-4702
ISSN:
1541-4337
Subject:
breakfast; consumer acceptance; dietary fiber; extrusion; fermentation; food industry; food safety; germination; hulling; lipid content; nutrient content; nutritive value; sensory evaluation
Abstract:
... Despite their high nutritional value and potential health benefits, pulse intake has not increased in the last three decades. Several strategies have been implemented to increase pulse consumption, such as their incorporation in bakery products, breakfast cereals, and snacks. The inclusion of pulses in these products could be an alternative to satisfy the consumers’ demand for healthy foods. Howev ...
DOI:
10.1111/1541-4337.12809

2. Black Bean Anthocyanin-Rich Extract from Supercritical and Pressurized Extraction Increased In Vitro Antidiabetic Potential, While Having Similar Storage Stability

Author:
Luis Mojica,   et al.   ; Ming Hsieh-Lo; Gustavo Castillo-Herrera;     Show all 3 Authors
Source:
Foods 2020 v.9 no.5 pp. -
ISSN:
2304-8158
Subject:
2,2-diphenyl-1-picrylhydrazyl; anthocyanins; antioxidant activity; black beans; chlorogenic acid; dipeptidyl-peptidase IV; ethanol; liquids; myricetin; rutin; storage quality; supercritical fluid extraction; syringic acid; ultra-performance liquid chromatography
Abstract:
... Black bean is a source of anthocyanins and other phenolic compounds that are associated with health benefits. This work aimed to optimize the extraction and determine the stability and biological potential of black bean anthocyanin-rich extracts recovered by supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE). The highest concentration of anthocyanins and total phenolic co ...
DOI:
10.3390/foods9050655

3. Cocoa (Theobroma cacao L.) Seed-Derived Peptides Reduce Blood Pressure by Interacting with the Catalytic Site of the Angiotensin-Converting Enzyme

Author:
Luis Mojica,   et al.   ; Luis Jorge Coronado-Cáceres; Blanca Hernández-Ledesma; Lucía Quevedo-Corona; Griselda Rabadán-Chávez; Gustavo Adolfo Castillo-Herrera; Eugenia Lugo Cervantes;     Show all 7 Authors
Source:
Foods 2021 v.10 no.10 pp. -
ISSN:
2304-8158
Subject:
Theobroma cacao; active sites; adults; computer simulation; diastolic blood pressure; diet; humans; ingredients; molecular weight; peptidyl-dipeptidase A; renin; systolic blood pressure
Abstract:
... This study aimed at determining the effect of cocoa proteins (CP) on the blood pressure, using in silico, in vitro and in vivo approaches. The in silico assay showed 26 Criollo cocoa peptides with alignment in the Blast® analysis. Peptide sequences ranged from 6 to 16 amino acids, with molecular weight ranging from 560.31 to 1548.76 Da. The peptide sequences LSPGGAAV, TSVSGAGGPGAGR, and TLGNPAAAGP ...
DOI:
10.3390/foods10102340

4. Common Bean Baked Snack Consumption Reduces Apolipoprotein B-100 Levels: A Randomized Crossover Trial

Author:
Luis Mojica,   et al.   ; Alejandro Escobedo; Edgar A. Rivera-León; Claudia Luévano-Contreras; Judith E. Urías-Silvas; Diego A. Luna-Vital; Norma Morales-Hernández;     Show all 7 Authors
Source:
Nutrients 2021 v.13 no.11 pp. -
ISSN:
2072-6643
Subject:
Phaseolus vulgaris; apolipoprotein B-100; beans; blood; blood lipids; chemical composition; cholesterol; cross-over studies; dietary fiber; glucose; hedonic scales; insulin; overweight; physical activity; popcorn; sensory evaluation
Abstract:
... Snack alternatives based on common beans (Phaseolus vulgaris L.) have been developed to promote pulse consumption. The purpose of this study was to evaluate the chemical composition, sensory acceptance and the effect of common bean baked snack (CBBS) consumption on blood lipid levels in participants with overweight and altered blood lipid levels. A sensory evaluation by 80 untrained judges was car ...
DOI:
10.3390/nu13113898

5. Thermal and enzymatic treatments reduced α‐galactooligosaccharides in common bean (Phaseolus vulgaris L.) flour

Author:
Luis Mojica,   et al.   ; Alejandro Escobedo; Carlos Mora;     Show all 3 Authors
Source:
Journal of food processing and preservation 2019 v.43 no.12 pp. e14273
ISSN:
0145-8892
Subject:
Phaseolus vulgaris; alpha-galactosidase; antinutritional factors; autoclaves; autoclaving; bean flour; carbohydrates; dietary fiber; endo-1,4-beta-glucanase; enzymatic treatment; flatulence; hydrolysis; ingredients; intestines; markets; nutrient content; nutritive value; pinto beans; soaking; tannins
Abstract:
... The aim of this study was to evaluate the effect of enzymatic, thermal, and soaking treatments on antinutritional factors as well as nutritional content of black and pinto beans to produce common bean flours. Black and pinto beans were soaked and treated with either enzymatic complex containing cellulase, hemicellulase, and β‐glucanase or thermally treated by autoclave. Black and pinto beans that ...
DOI:
10.1111/jfpp.14273

6. Food-derived bioactive compounds with anti-aging potential for nutricosmetic and cosmeceutical products

Author:
Luis Mojica,   et al.   ; David Fonseca Hernandez; Eugenia Lugo Cervantes; Diego A. Luna-Vital;     Show all 4 Authors
Source:
Critical reviews in food science and nutrition 2021 v.61 no.22 pp. 3740-3755
ISSN:
1549-7852
Subject:
antioxidants; cosmetics; food science; humans; industry; inflammation; markets; mechanism of action; nutrition; phytochemicals; radiation resistance; ultraviolet radiation
Abstract:
... Besides providing essential nutrients for humans, food contains bioactive compounds that exert diverse biological activities such as anti-microbial, anti-cancerogenic, anti-viral, anti-inflammatory and antioxidant. The cosmetic industry is interested in natural bioactive compounds for their use in nutricosmetic and cosmeceutical products. These products aimed to reduce skin aging, inflammation or ...
DOI:
10.1080/10408398.2020.1805407

7. Lutein as a functional food ingredient: Stability and bioavailability

Author:
Luis Mojica Contreras,   et al.   ; Mario Ochoa Becerra; Ming Hsieh Lo; Juan Mateos Díaz; Gustavo Castillo Herrera;     Show all 5 Authors
Source:
Journal of functional foods 2020 v.66 pp. 103771
ISSN:
1756-4646
Subject:
algae; antioxidant activity; bacteria; bioavailability; brain; food composition; food matrix; functional foods; infants; ingredients; lutein; macular degeneration; neoplasms; yeasts
Abstract:
... Lutein is a carotenoid found in numerous organisms ranging from bacteria to algae, yeasts, and plants. The biological importance of this pigment emerged from various studies demonstrating its antioxidant potential, playing a significant role in the prevention of age-related macular degeneration and other diseases such as cancer. Lutein is also essential in the development of infants brain and must ...
DOI:
10.1016/j.jff.2019.103771

8. Technological Applications of Natural Colorants in Food Systems: A Review

Author:
Luis Mojica,   et al.   ; Ivan Luzardo-Ocampo; Aurea K. Ramírez-Jiménez; Jimena Yañez; Diego A. Luna-Vital;     Show all 5 Authors
Source:
Foods 2021 v.10 no.3 pp. -
ISSN:
2304-8158
Subject:
color; extraction; information; research
Abstract:
... Natural colorants have emerged as an alternative to their synthetic counterparts due to an existing health concern of these later. Moreover, natural-food colorants are a renewable option providing health benefits and interesting technological and sensory attributes to the food systems containing them. Several sources of natural colorants have been explored aiming to deliver the required wide color ...
DOI:
10.3390/foods10030634

9. Combinations of Legume Protein Hydrolysates Synergistically Inhibit Biological Markers Associated with Adipogenesis

Author:
Luis Mojica,   et al.   ; Cecilia Moreno; Elvira González de Mejía; Rosa María Camacho Ruiz; Diego A. Luna-Vital;     Show all 5 Authors
Source:
Foods 2020 v.9 no.11 pp. -
ISSN:
2304-8158
Subject:
adipogenesis; antioxidants; black beans; chickpeas; computer simulation; energy; faba beans; hydrolysis; legume protein; lentils; nitric oxide; pancreatin; peas; pepsin; peptides; subtilisin; triacylglycerol lipase
Abstract:
... The objective was to investigate the anti-adipogenesis potential of selected legume protein hydrolysates (LPH) and combinations using biochemical assays and in silico predictions. Black bean, green pea, chickpea, lentil and fava bean protein isolates were hydrolyzed using alcalase (A) or pepsin/pancreatin (PP). The degree of hydrolysis ranged from 15.5% to 35.5% for A-LPH and PP-LPH, respectively. ...
DOI:
10.3390/foods9111678

10. Cocoa (Theobroma cacao L.) Seed Proteins’ Anti-Obesity Potential through Lipase Inhibition Using In Silico, In Vitro and In Vivo Models

Author:
Luis Mojica,   et al.   ; Luis Jorge Coronado-Cáceres; Griselda Rabadán-Chávez; Blanca Hernández-Ledesma; Lucía Quevedo-Corona; Eugenia Lugo Cervantes;     Show all 6 Authors
Source:
Foods 2020 v.9 no.10 pp. -
ISSN:
2304-8158
Subject:
Theobroma cacao; absorption; albumins; animal models; computer simulation; excretion; feces; foods; hepatotoxicity; high fat diet; humans; hydrolysates; hydrolysis; intestinal absorption; intragastric administration; metabolism; peptides; prediction; probability; rats; triacylglycerol lipase; triacylglycerols; vicilin
Abstract:
... The aim of this study was to determine the pancreatic lipase (PL) inhibitory effect of cocoa protein (CP) hydrolysates (CPH) using in silico and in vitro approaches, and an in vivo high-fat diet (HF) obese rat model. The results showed better theoretical affinity on PL for cocoa peptides EEQR, GGER, QTGVQ, and VSTDVNIE released from vicilin and albumins (-6.5, -6.3, -6.2, and -6.1 kcal/mol, respec ...
DOI:
10.3390/foods9101359

11. Phycocyanin and phycoerythrin: Strategies to improve production yield and chemical stability

Author:
Luis Mojica,   et al.   ; Ming Hsieh-Lo; Gustavo Castillo; Mario Alberto Ochoa-Becerra;     Show all 4 Authors
Source:
Algal research 2019 v.42 pp. 101600
ISSN:
2211-9264
Subject:
biomass; color; commercialization; cosmetics; dietary supplements; fluorescence; foods; microalgae; microorganisms; natural dyes; photosynthesis; phycocyanin; phycoerythrin; pigments; wavelengths
Abstract:
... Phycocyanin and phycoerythrin are photosynthetic pigments extracted from microalgae with great biotechnological potential due to their intense colors, fluorescent properties and potential health benefits. Their principal applications are as nutritional supplements, natural colorants in foods and cosmetics, and as a reagent for immunological assays. However, the main challenges for their commercial ...
DOI:
10.1016/j.algal.2019.101600

12. Potential Health Benefits Associated with Lunasin Concentration in Dietary Supplements and Lunasin-Enriched Soy Extract

Author:
Luis Mojica,   et al.   ; Elvira Gonzalez de Mejia; Erick Damian Castañeda-Reyes; Vermont Dia; Hui Wang; Toni Wang; Lawrence A. Johnson;     Show all 7 Authors
Source:
Nutrients 2021 v.13 no.5 pp. -
ISSN:
2072-6643
Subject:
antioxidant activity; chemoprevention; dose response; histone acetyltransferase; melanoma; non-specific serine/threonine protein kinase; ultrafiltration
Abstract:
... Lunasin has demonstrated antioxidative, anti-inflammatory, and chemopreventive properties. The objectives were to evaluate the concentration of lunasin in different lunasin-based commercial dietary supplements, to produce a lunasin-enriched soy extract (LESE) using a two-step pilot-plant-based ultrafiltration process, and to evaluate their biological potential in vitro. LESE was produced using 30 ...
DOI:
10.3390/nu13051618

13. Autoclaving and extrusion improve the functional properties and chemical composition of black bean carbohydrate extracts

Author:
Luis Mojica,   et al.   ; Alejandro Escobedo; Guadalupe Loarca‐Piña; Marcela Gaytan‐Martínez; Ignacio Orozco‐Avila;     Show all 5 Authors
Source:
Journal of food science 2020 v.85 no.9 pp. 2783-2791
ISSN:
0022-1147
Subject:
Phaseolus vulgaris; amylose; autoclaving; black beans; color; dietary fiber; enthalpy; extrusion; fiber content; food science; hulling; resistant starch; temperature
Abstract:
... Common beans (Phaseolus vulgaris L.) are rich in starch with a high content of amylose, which is associated with the production of retrograded and pregelatinized starch through thermal treatments. The purpose of this study was to evaluate the composition, morphology, thermal, functional, and physicochemical properties of carbohydrate extracts (CE) obtained from autoclaved (100 and 121 °C) and extr ...
DOI:
10.1111/1750-3841.15356

14. Bioactive proteins and phytochemicals from legumes: Mechanisms of action preventing obesity and type-2 diabetes

Author:
Luis Mojica,   et al.   ; Cecilia A. Moreno-Valdespino; Diego Luna-Vital; Rosa M. Camacho-Ruiz;     Show all 4 Authors
Source:
Food research international 2020 v.130 pp. 108905
ISSN:
0963-9969
Subject:
Fabaceae; bioactive compounds; bioactive properties; color; in vivo studies; legumes; mechanism of action; noninsulin-dependent diabetes mellitus; obesity; peptides; phytochemicals; proteins; risk reduction; seeds
Abstract:
... The Fabaceae family of plants include a variety of seeds with multiple shapes, sizes, and colors; with a great diversity of bioactive compounds found in legume seeds. Legumes are an excellent source of protein, peptides and phytochemicals which are present in significant amounts. These bioactive compounds have been reported to reduce the risk of developing non-communicable diseases (NCD), such as ...
DOI:
10.1016/j.foodres.2019.108905

15. Bioactive Peptides from Black Bean Proteins Play a Potential Role in the Prevention of Adipogenesis (P06-119-19)

Author:
Luis Mojica,   et al.   ; Cecilia Moreno Valdespino; Elvira Gonzalez de Mejia; Diego Luna-Vital; Rosa Camacho;     Show all 5 Authors
Source:
Current developments in nutrition 2019 v.3 no.Supplement_1 pp. -
ISSN:
2475-2991
Subject:
adipocytes; adipogenesis; angiotensin-converting enzyme inhibitors; bioactive properties; black beans; databases; dose response; electrospray ionization mass spectrometry; food matrix; functional foods; hydrolysates; in vitro digestion; inhibitory concentration 50; lipid metabolism; liquid chromatography; obesity; pancreatin; pepsin; peptides; physical properties; polyacrylamide gel electrophoresis; protein composition; protein hydrolysates; protein isolates; risk reduction; staining; subtilisin; triacylglycerol lipase; triacylglycerols
Abstract:
... Food-based products such as common bean peptides may contribute to reduce the risk of complications associated with obesity. The objective of this research was to produce and characterize peptides from common bean protein isolates and evaluate their potential to prevent adipogenesis. Protein hydrolysates of raw common black bean (BBPH) were generated using a simulated gastrointestinal digestion by ...
DOI:
10.1093/cdn/nzz031.P06-119-19

16. Black bean peptides inhibit glucose uptake in Caco-2 adenocarcinoma cells by blocking the expression and translocation pathway of glucose transporters

Author:
Luis Mojica,   et al.   ; Diego A. Luna-Vital; Elvira Gonzalez de Mejia;     Show all 3 Authors
Source:
Toxicology reports 2018 v.5 pp. 552-560
ISSN:
2214-7500
Subject:
adenocarcinoma; adjuvants; black beans; colorectal neoplasms; fluorescence microscopy; gene expression; glucose; ingredients; peptides; protein synthesis; toxicology
Abstract:
... The objective was to evaluate the effect of black bean protein fraction (PFRA), and its derived peptides on glucose uptake, SGLT1 and GLUT2 expression and translocation on Caco-2 cells. The effect of treatments was evaluated on glucose uptake, protein expression and localization and gene expression on Caco-2 cells. PFRA (10 mg/mL) lowered glucose uptake from 27.4% after 30 min to 33.9% after 180 m ...
DOI:
10.1016/j.toxrep.2018.04.007
CHORUS:
10.1016/j.toxrep.2018.04.007

17. Nutritional, Antinutritional Compounds and Nutraceutical Significance of Native Bean Species (Phaseolus spp.) of Mexican Cultivars

Author:
Luis Mojica,   et al.   ; Montserrat Alcázar-Valle; Soledad García-Morales; Norma Morales-Hernández; Ever Sánchez-Osorio; Lourdes Flores-López; Jhony Navat Enríquez-Vara; Eugenia Lugo-Cervantes;     Show all 8 Authors
Source:
Agriculture (Basel) 2021 v.11 no.11 pp. -
ISSN:
2077-0472
Subject:
Phaseolus coccineus; Phaseolus lunatus; Phaseolus vulgaris; agriculture; antioxidant activity; beans; cultivars; dietary supplements; free amino acids; isoleucine; lipid content; nutrient content; principal component analysis; tryptophan; Mexico
Abstract:
... Common beans (Phaseolus vulgaris), comba beans (Phaseolus lunatus), and ayocote beans (Phaseolus coccineus) are the most consumed beans worldwide. This work aimed to analyze the nutraceutical potential, antinutritional content, antioxidant activity, and physicochemical characteristics of 38 native bean accessions from South Pacific Mexico. Regarding size, the accessions collected from P. lunatus w ...
DOI:
10.3390/agriculture11111031

18. Chia Seed (Salvia hispanica L.) Pepsin Hydrolysates Inhibit Angiotensin‐Converting Enzyme by Interacting with its Catalytic Site

Author:
Luis Mojica,   et al.   ; Brenda San Pablo‐Osorio; Judith Esmeralda Urías‐Silvas;     Show all 3 Authors
Source:
Journal of food science 2019 v.84 no.5 pp. 1170-1179
ISSN:
0022-1147
Subject:
Salvia hispanica; active sites; chymotrypsin; energy; enzyme inhibition; fats and oils industry; hydrolysates; hydrolysis; hypertension; industrial byproducts; ingredients; inhibitory concentration 50; pepsin; peptides; peptidyl-dipeptidase A; protein hydrolysates; protein isolates; seed oils; subtilisin; trypsin; wastes
Abstract:
... High blood pressure can lead to cardiovascular diseases. The objective of this work was to obtain protein hydrolysates with antihypertensive potential from chia oil industry meal byproduct. Chia seed protein isolates (CPIs) were obtained from chia seed meal byproduct. CPI was hydrolyzed using different proteases (alcalase, pepsin, trypsin, and α‐chymotrypsin) and their biological potential was eva ...
DOI:
10.1111/1750-3841.14503

19. Black bean anthocyanin-rich extracts as food colorants: Physicochemical stability and antidiabetes potential

Author:
Luis Mojica,   et al.   ; Mark Berhow; Elvira Gonzalez de Mejia;     Show all 3 Authors
Source:
Food chemistry 2017 v.229 pp. 628-639
ISSN:
0308-8146
Subject:
alpha-amylase; alpha-glucosidase; anthocyanins; black beans; dipeptidyl-peptidase IV; dyes; ethanol; food coloring; foods; glucose; half life; ions; pH; phenolic compounds; reactive oxygen species
Abstract:
... Black beans contain anthocyanins that could be used as colorants in foods with associated health benefits. The objective was to optimize anthocyanins extraction from black bean coats and evaluate their physicochemical stability and antidiabetes potential. Optimal extraction conditions were 24% ethanol, 1:40 solid-to-liquid ratio and 29°C (P<0.0001). Three anthocyanins were identified by MS ions, d ...
Handle:
10113/5639762
DOI:
10.1016/j.foodchem.2017.02.124

20. Anti-obesity effect of cocoa proteins (Theobroma cacao L.) variety “Criollo” and the expression of genes related to the dysfunction of white adipose tissue in high-fat diet-induced obese rats

Author:
Luis Mojica,   et al.   ; Luis Jorge Coronado-Cáceres; Griselda Rabadán-Chávez; Lucía Quevedo-Corona; Blanca Hernández-Ledesma; Angel Miliar Garcia; Eugenia Lugo-Cervantes;     Show all 7 Authors
Source:
Journal of functional foods 2019 pp. -
ISSN:
1756-4646
Subject:
Theobroma cacao; animal disease models; blood serum; body weight changes; cocoa beans; energy expenditure; free fatty acids; gene expression; genes; high density lipoprotein; high energy diet; high fat diet; insulin; leptin; lipogenesis; messenger RNA; obesity; peroxisome proliferator-activated receptor alpha; peroxisome proliferator-activated receptor gamma; rats; triacylglycerols; tumor necrosis factor-alpha; white adipose tissue
Abstract:
... The objective of this work was to evaluate if Cocoa Proteins (CP) from the cocoa-bean were able to reduce factors related to obesity and activated related gene targets against white adipose tissue (WAT) dysfunction in a rat model of hypercaloric diet-induced obesity. The results showed that the administration with 150 mg/kg/day of CP on a hypercaloric diet reduces body-weight gain, relative weight ...
DOI:
10.1016/j.jff.2019.103519