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- Lukat, Peer, et al. Show all 5 Authors
- Journal of the American Chemical Society 2019 v.141 no.17 pp. 6906-6914
- Chlorobium limicola; active sites; anaerobic conditions; bacteria; biosynthesis; catalytic activity; chemical bonding; crystal structure; histidine; humans; metabolites; reactive oxygen species; virulent strains
- ... Ergothioneine is an emergent factor in cellular redox biochemistry in humans and pathogenic bacteria. Broad consensus has formed around the idea that ergothioneine protects cells against reactive oxygen species. The recent discovery that anaerobic microorganisms make the same metabolite using oxygen-independent chemistry indicates that ergothioneine also plays physiological roles under anoxic cond ...