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- Lyon, Mary F.
- Mammalian genome 2000 v.11 no.10 pp. 817-819
- genes; heterozygosity; males; meiotic drive; mice
- ... The t-complex is maintained in wild mouse populations by its high transmission (up to 99%) from heterozygous males and provides an example of ``meiotic drive''. Its molecular basis has remained obscure despite long and intensive study. In a major advance, the t-complex responder gene, thought to be the key gene on which several distorters act, has now been cloned. ...
- Lyon, Mary F., et al. Show all 7 Authors
- Mammalian genome 1999 v.10 no.6 pp. 617-622
- alternative splicing; complementary DNA; chromosomes; brain; mutation; cell division; mice; cDNA libraries; exons; microtubules; mitochondria; screening; Northern blotting; kinesin; cytoplasmic streaming
- ... Kinesin and kinesin superfamily proteins are molecular motors involved in important intracellular functions such as organelle transport and cell division. They are microtubule-activated ATPases composed of a motor domain that binds to microtubules and a cargo-binding domain that binds to specific organelles. While searching for the slow Wallerian degeneration mutation (Wld S ) on distal mouse Chro ...