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- Martin, Rebecca K., et al. Show all 3 Authors
- Biochemical and biophysical research communications 2019 v.512 no.4 pp. 723-728
- immune response; interleukin-5; lymphocytes; metalloproteinases; protein content
- ... Group 2 innate lymphoid cells (ILC2s) play an important role in the initiation of type-2 immune responses. Numerous targets have been identified that may activate or repress ILC2 function, though few negative regulatory feedback pathways induced upon activation have been shown to be operative in ILC2s. Here we demonstrate that loss of ADAM17 from ILC2s results in a selective defect in IL-33 respon ...