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- Matsuda, Hiromi, et al. Show all 9 Authors
- Life sciences 2015 v.142 pp. 1-7
- Escherichia coli; diaphragm; inflammation; intraperitoneal injection; knockout mutants; lipopolysaccharides; mice; models; pathophysiology; peritonitis; prostaglandin synthase; prostaglandins; vascular endothelial growth factors
- ... Lymphangiogenesis is frequently observed during inflammation, and this inflammation-induced lymphangiogenesis (IL) is a phenomenon actively involved in the pathophysiology of inflammation. We explored the roles of an inducible prostaglandin E synthase, mPGES-1, in IL elicited by lipopolysaccharide (LPS).Peritonitis was induced in mice by intraperitoneal injection of LPS (E. coli 0111-B4; 25μg/mous ...
- Matsuda, Hiromi, et al. Show all 15 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2011 v.108 no.25 pp. 10349-10354
- brain; cell viability; cysteine; enzyme activity; mice; nitric oxide; proteins; screening; sequence homology; support systems
- ... Nitric oxide (NO) physiologically regulates numerous cellular responses through S-nitrosylation of protein cysteine residues. We performed antibody-array screening in conjunction with biotin-switch assays to look for S-nitrosylated proteins. Using this combination of techniques, we found that phosphatase with sequence homology to tensin (PTEN) is selectively S-nitrosylated by low concentrations of ...
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