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- Mitrović, Ana, et al. Show all 4 Authors
- Biochimie 2019
- angiogenesis; antineoplastic agents; apoptosis; carcinogenesis; cathepsins; cystatins; cysteine; enzyme activity; immune response; metastasis; neoplasms; therapeutics
- ... Cystatins are endogenous and reversible inhibitors of cysteine peptidases that are important players in cancer progression. Besides their primary role as regulators of cysteine peptidase activity, cystatins are involved in cancer development and progression through proteolysis-independent mechanisms. Mechanistic studies of cystatin function revealed that they affect all stages of cancer progressio ...