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- Author:
- Rodríguez-Blanco, M.; Ramos, A.J.; Sanchis, V.; Marín, S.
- Source:
- Fungal biology 2021 v.125 no.2 pp. 103-114
- ISSN:
- 1878-6146
- Subject:
- Monascus, etc ; European Union; Fusarium; Geotrichum; Penicillium; aflatoxins; corn silage; dairy cows; farms; feed contamination; fumonisins; fungi; lactic acid bacteria; water activity; Spain; Show all 15 Subjects
- Abstract:
- ... Silages constitute a major component of the feed ration for dairy cows, being a potential source of mycotoxins due to the possible contamination by filamentous fungi capable of producing these toxic compounds. In this study, samples of different kinds of silages collected from farms located in four regions of Spain, were analysed to evaluate the occurrence of aflatoxins (AFs) and Fusarium mycotoxi ...
- DOI:
- 10.1016/j.funbio.2019.08.006
-
https://dx.doi.org/10.1016/j.funbio.2019.08.006
- Author:
- Wang, Pan; Chen, Shuqiong; Wei, Chengye; Yan, Qingpi; Sun, Yun-Zhang; Yi, Ganfeng; Li, Dong; Fu, Weilai
- Source:
- Aquaculture 2021 v.530 pp. 735947
- ISSN:
- 0044-8486
- Subject:
- Monascus purpureus, etc ; Lactobacillus; Litopenaeus vannamei; amylases; antioxidant activity; disease resistance; feed additives; fermented foods; glutathione peroxidase; growth performance; histology; immune response; intestinal microorganisms; intestines; multidimensional scaling; red yeast rice; shrimp; superoxide dismutase; traditional foods; villi; Show all 20 Subjects
- Abstract:
- ... Monascus purpureus M-32 was successfully isolated from the Chinese traditional food red mould rice, and its fermentation product was supplemented in the diet of Litopenaeus vannamei at different concentrations (T0: 0 g/kg; T1: 5 g/kg; T2: 10 g/kg and T3: 20 g/kg). After 8 weeks, the dietary administration of the M-32 fermentation product significantly decreased the FCR in groups T1 and T2 and sign ...
- DOI:
- 10.1016/j.aquaculture.2020.735947
-
https://dx.doi.org/10.1016/j.aquaculture.2020.735947
- Author:
- Xiang, Xingliang; Song, Chengwu; Shi, Qingxin; Tian, Ji; Chen, Cheng; Huang, Jiaxin; She, Bo; Zhao, Xueyan; Huang, Rongzeng; Jin, Shuna
- Source:
- Food chemistry 2020 v.331 pp. 127281
- ISSN:
- 0308-8146
- Subject:
- Monascus purpureus, etc ; Eurotium; bioavailability; fungi; metabolomics; turmeric; Show all 6 Subjects
- Abstract:
- ... Curcuminoids are the major bioactive constituents of turmeric, the application of which are limited by the poor bioavailability. In this study, turmeric was fermented by the Monascus purpureus and Eurotium cristatum fungi to enhance its bioavailability. To explore the variations in the curcuminoids contents in fermented turmeric, a targeted predict-verify strategy was established. For targeted ana ...
- DOI:
- 10.1016/j.foodchem.2020.127281
-
https://dx.doi.org/10.1016/j.foodchem.2020.127281
- Author:
- Cheng, Ming-Jen; Wu, Ho-Cheng; Wu, Ming-Der; Hsun-Hsuo-Chang,
- Source:
- Chemistry of natural compounds 2020 v.56 no.2 pp. 286-288
- ISSN:
- 0009-3130
- Subject:
- Monascus, etc ; fungi; mass spectrometry; nuclear magnetic resonance spectroscopy; phytochemicals; pyrroles; Show all 6 Subjects
- Abstract:
- ... A phytochemical investigation of the fungus Monascus floridanus resulted in a novel pyrrole compound, floridapyrrole. The structure of the new compound was identified by 1D, 2D NMR (COSY, NOESY, HSQC, and HMBC), mass spectrometry, and IR spectra. ...
- DOI:
- 10.1007/s10600-020-03008-z
-
http://dx.doi.org/10.1007/s10600-020-03008-z
- Author:
- Isbrandt, Thomas; Tolborg, Gerit; Ødum, Anders; Workman, Mhairi; Larsen, Thomas Ostenfeld
- Source:
- Applied microbiology and biotechnology 2020 v.104 no.2 pp. 615-622
- ISSN:
- 0175-7598
- Subject:
- Monascus, etc ; Talaromyces; amino acids; carboxylic acids; fermentation; fungi; isomers; pigments; Show all 8 Subjects
- Abstract:
- ... A new series of azaphilone pigments named atrorosins have been isolated from the filamentous fungus Talaromyces atroroseus. Atrorosins have a similar azaphilone scaffold as the orange Monascus pigment PP-O, with a carboxylic acid group at C-1, but are unique by their incorporation of amino acids into the isochromene system. Despite that the atrorosin precursor PP-O, during fermentation, was initia ...
- DOI:
- 10.1007/s00253-019-10216-3
-
https://dx.doi.org/10.1007/s00253-019-10216-3
- Author:
- Zhang, Chan; Zhu, Qianqian; Zhang, Han; Zhang, Nan; Yang, Xuelian; Shi, Jiachen; Sun, Baoguo; Wang, Chengtao
- Source:
- Fungal biology 2020 v.124 no.7 pp. 661-670
- ISSN:
- 1878-6146
- Subject:
- Monascus purpureus, etc ; biosynthesis; cholesterol; gene deletion; gene overexpression; humans; lovastatin; mycelium; secondary metabolites; sporulation; Show all 10 Subjects
- Abstract:
- ... Monacolin K is a secondary metabolite of Monascus and is known to decrease cholesterol levels in humans. There are 9 genes (mokA-mokI) controlling its biosynthesis, of which mokH is thought to act as a pathway-specific regulator. In this study, the Monascus purpureus M1 strain was compared with mokH gene deletion strains (△H1) and overexpression strains (H7). The monacolin K yields in the △H1 stra ...
- DOI:
- 10.1016/j.funbio.2020.03.010
-
https://dx.doi.org/10.1016/j.funbio.2020.03.010
- Author:
- Long, Chuannan; Cui, Jingjing; Xie, Shaobin; Zhang, Dongsheng; Liu, Mengmeng; Zhang, Zhe; Huang, Zhiwei; Zeng, Bin
- Source:
- 3 Biotech 2020 v.10 no.2 pp. 45
- ISSN:
- 2190-572X
- Subject:
- Monascus ruber, etc ; Aspergillus oryzae; alpha-amylase; glycosides; hydrolysis; introns; phylogeny; pigments; rice; rice starch; starch; Show all 11 Subjects
- Abstract:
- ... Previously, AoamyA, the alpha amylase-encoding gene from Aspergillus oryzae, was heterologously expressed in Monascus ruber CICC41233 to promote starch hydrolysis and increase the production of Monascus pigments. The target of this study is to screen the effective alpha-amylases from M. ruber for starch fast degradation and investigated for Monascus pigments production. The 13 types of predicted a ...
- DOI:
- 10.1007/s13205-019-2026-8
- PubMed:
- 31988839
- PubMed Central:
- PMC6954919
-
https://dx.doi.org/10.1007/s13205-019-2026-8
- Author:
- Wu, Ho-Cheng; Chen, Jih-Jung; Wu, Ming-Der; Cheng, Ming-Jen; Chang, Hsun-Shuo
- Source:
- Phytochemistry letters 2020 v.40 pp. 181-187
- ISSN:
- 1874-3900
- Subject:
- Monascus pilosus, etc ; anti-inflammatory activity; color; fungi; macrophages; mice; mutants; mycelium; quercetin; red yeast rice; rice; secondary metabolites; Show all 12 Subjects
- Abstract:
- ... Red yeast rice was used over than thousands of years, containing abundant secondary metabolites with different bioactivities. Nowadays, the investigation of Monascus spp. was changed from anti-cholesterol monacolin analogues to Monascus pigments. Monascus pilosus BCRC38072 is a citrinin-free red yeast rice from yellow mutant of mycelia, which was already sequenced and assembled. The EtOAc-soluble ...
- DOI:
- 10.1016/j.phytol.2020.04.014
-
https://dx.doi.org/10.1016/j.phytol.2020.04.014
- Author:
- Morales-Oyervides, Lourdes; Ruiz-Sánchez, Juan Pablo; Oliveira, Jorge C.; Sousa-Gallagher, María Jose; Méndez-Zavala, Alejandro; Giuffrida, Daniele; Dufossé, Laurent; Montañez, Julio
- Source:
- Biotechnology advances 2020 v.43 pp. 107601
- ISSN:
- 0734-9750
- Subject:
- Monascus, etc ; Penicillium; Talaromyces; bioprocessing; food additives; fungal pigments; industrial applications; natural dyes; research and development; toxicity; Asia; Show all 11 Subjects
- Abstract:
- ... There has been an increased interest in replacing synthetic colorants by colorants obtained from natural sources, especially microbial pigments.Monascus pigments have been used as natural colorings and food additives in Asia for centuries but have raised toxicity issues. Recently, Talaromyces/Penicillium species have been recognized as potential strains to produce natural pigments similar to those ...
- DOI:
- 10.1016/j.biotechadv.2020.107601
-
https://dx.doi.org/10.1016/j.biotechadv.2020.107601
- Author:
- Erkaya, Seval; Arslan, Nazli Pinar; Orak, Tugba; Esim, Nevzat; Taskin, Mesut
- Source:
- Journal of basic microbiology 2020 v.60 no.8 pp. 669-678
- ISSN:
- 0233-111X
- Subject:
- Monascus purpureus, etc ; cell growth; citric acid; citrinin; ethanol; farnesol; lactic acid; metabolites; pigments; prices; quorum sensing; synthesis; toxicity; Show all 13 Subjects
- Abstract:
- ... This study focused on investigating the effect of exogenously applied two quorum sensing molecules (tyrosol and farnesol) on the synthesis of bioactive metabolites (pigments, lactic acid, ethanol, and citric acid) in Monascus purpureus ATCC16365. None of the tested concentrations (62.5, 125, 250, and 500 µl/L) of farnesol affected the synthesis of metabolites as well as cell growth. As with farnes ...
- DOI:
- 10.1002/jobm.202000037
-
http://dx.doi.org/10.1002/jobm.202000037
- Author:
- Zhang, Yaru; Chen, Zhiting; Wen, Qinyou; Xiong, Zixiao; Cao, Xiaohua; Zheng, Zhenghuai; Zhang, Yangxin; Huang, Zhiwei
- Source:
- Food & function 2020 v.11 no.7 pp. 5738-5748
- ISSN:
- 2042-650X
- Subject:
- Monascus, etc ; Aspergillus terreus; biochemical pathways; biosynthesis; cholesteremic effect; depth; exhibitions; fungi; lovastatin; metabolic engineering; multigene family; research; synthesis; Show all 13 Subjects
- Abstract:
- ... Lovastatin/monacolin K (MK) is used as a lipid lowering drug, due to its effective hypercholesterolemic properties, comparable to synthetic statins. Lovastatin's biosynthetic pathway and gene cluster composition have been studied in depth in Aspergillus terreus. Evidence shows that the MK biosynthetic pathway and gene cluster in Monascus sp. are similar to those of lovastatin in A. terreus. Curren ...
- DOI:
- 10.1039/d0fo00691b
-
http://dx.doi.org/10.1039/d0fo00691b
- Author:
- Xu, Dandan; Wang, Peng; Zhang, Xin; Zhang, Jian; Sun, Yong; Gao, Lihua; Wang, Wenping
- Source:
- Food microbiology 2020 v.86
- ISSN:
- 0740-0020
- Subject:
- Monascus, etc ; Acinetobacter; Actinomucor; Aspergillus; Enterobacter; Trichosporon; amino nitrogen; bacterial communities; fermentation; fungi; high-throughput nucleotide sequencing; pH; soybeans; traditional foods; Show all 14 Subjects
- Abstract:
- ... Red sufu is a traditional food produced by the fermentation of soybean. In this study, sufu samples were periodically collected during the whole fermentation to investigate the dynamic changes of fungal and bacterial communities using high-throughput sequencing technology. The overall process can be divided into pre- and post-fermentation. During post-fermentation, the pH value showed a gradual de ...
- DOI:
- 10.1016/j.fm.2019.103340
-
https://dx.doi.org/10.1016/j.fm.2019.103340
- Author:
- Zhang, Chan; Zhang, Han; Zhu, Qianqian; Hao, Shuai; Chai, Shiyuan; Li, Yinghui; Jiao, Zi; Shi, Jiachen; Sun, Baoguo; Wang, Chengtao
- Source:
- Applied microbiology and biotechnology 2020 v.104 no.7 pp. 3049-3060
- ISSN:
- 0175-7598
- Subject:
- Monascus purpureus, etc ; fungi; gene overexpression; genes; high performance liquid chromatography; lovastatin; mycelium; pigments; scanning electron microscopy; secondary metabolites; spectrophotometers; Show all 11 Subjects
- Abstract:
- ... Monascus is a filamentous fungus that produces several secondary metabolites. Here, we investigated the effects of the global regulator LaeA on the synthesis of pigments and monacolin K in Monascus purpureus with spectrophotometer and HPLC methods. The LaeA gene was isolated from M. purpureus M1 to create an overexpression construct. An LaeA-overexpressing strain L3 was with 48.6% higher monacolin ...
- DOI:
- 10.1007/s00253-020-10379-4
-
http://dx.doi.org/10.1007/s00253-020-10379-4
- Author:
- Marič, Ajda; Skočaj, Matej; Likar, Matevž; Sepčić, Kristina; Cigić, Irena Kralj; Grundner, Maja; Gregori, Andrej
- Source:
- Journal of food science and technology 2019 v.56 no.7 pp. 3364-3373
- ISSN:
- 0022-1155
- Subject:
- Monascus purpureus, etc ; brown rice; citrinin; detection limit; lovastatin; millets; pigments; Show all 7 Subjects
- Abstract:
- ... Six Monascus purpureus (red mould) strains were cultivated on brown rice and millet as substrates. They underwent strain selection for high lovastatin and pigment production, and low citrinin mycotoxin production, with particular reference to potential for millet as substrate. For most of these strains, substrate dry matter loss was 54–60% on rice and 46–48% on millet, although the ‘MOPU GS1’ stra ...
- DOI:
- 10.1007/s13197-019-03820-8
- PubMed:
- 31274904
- PubMed Central:
- PMC6582186
-
http://dx.doi.org/10.1007/s13197-019-03820-8
- Author:
- de Oliveira, Camila Fernanda Dias; da Costa, Jaquelinne Pires Vital; Vendruscolo, Francielo
- Source:
- Biocatalysis and agricultural biotechnology 2019 v.18 pp. 101101
- ISSN:
- 1878-8181
- Subject:
- Monascus ruber, etc ; byproducts; fungi; industry; maltose; pH; pigments; syrups; Show all 8 Subjects
- Abstract:
- ... The objective of this study was to determine the effect of pH on the growth rate and production of pigments by Monascus ruber from maltose syrup residue as a substrate. The cultivations were carried out in solid and submerged media under different pH conditions. The highest radial growth rate occurred when the Monascus ruber was cultivated at pH 6.5 and the production of yellow pigments occurred a ...
- DOI:
- 10.1016/j.bcab.2019.101101
-
https://dx.doi.org/10.1016/j.bcab.2019.101101
- Author:
- Li, Yanping; Wang, Na; Jiao, Xuexue; Tu, Zhui; He, Qinghua; Fu, Jinheng
- Source:
- Journal of basic microbiology 2020 v.60 no.10 pp. 873-881
- ISSN:
- 0233-111X
- Subject:
- Monascus, etc ; acetyl coenzyme A; carbon; citrinin; fructose-2,6-bisphosphate 2-phosphatase; gene targeting; genes; glycolysis; malonyl coenzyme A; microbiology; polymerase chain reaction; synthesis; Show all 12 Subjects
- Abstract:
- ... The application of Monascus is restricted by citrinin. So, it is important to explore the synthetic pathway of citrinin to completely inhibit the production of citrinin. In our previous study, we found that the protein encoded by the ctnF gene has a significant similarity to fructose‐2,6‐bisphosphatase (F26BPase). It is generally known that the bifunctional enzyme F26BPase regulates the glycolytic ...
- DOI:
- 10.1002/jobm.202000059
-
http://dx.doi.org/10.1002/jobm.202000059
- Author:
- He, Shanshan; Liu, Xin; Wang, Yanling; Xie, Jianhua; Gao, Heng; Li, Xiujiang; Huang, Zhibing
- Source:
- Lebensmittel-Wissenschaft + [i.e. und] Technologie 2020 v.130 pp. 109613
- ISSN:
- 0023-6438
- Subject:
- Monascus, etc ; aspartic acid; bioactive compounds; citrinin; ergosterol; fermentation; genistein; glutamic acid; lovastatin; lysine; metabolites; metabolomics; pyruvic acid; quality control; tandem mass spectrometry; tricarboxylic acid cycle; Show all 16 Subjects
- Abstract:
- ... Monascus mold produces useful bioactive compounds such as Monascus pigments, monacolin K, and ergosterol. In this study, metabolomics analysis was used to investigate the metabolic profile changes in Monascus aurantiacus Li AS3.4384 (MALA) induced by genistein at different fermentation times using UHPLC-Q-TOF-MS/MS. The addition of genistein was found to not only reduce citrinin but also suppress ...
- DOI:
- 10.1016/j.lwt.2020.109613
-
https://dx.doi.org/10.1016/j.lwt.2020.109613
- Author:
- Zhang, Xiaowei; Liu, Chunhui; Tian, Wenhan; Zhang, Hui; Li, Peirui; Wang, Jiahua; He, Weiwei
- Source:
- Food & function 2020 v.11 no.7 pp. 5915-5923
- ISSN:
- 2042-650X
- Subject:
- Monascus, etc ; 2,2-diphenyl-1-picrylhydrazyl; antioxidant activity; density functional theory; dose response; electron paramagnetic resonance spectroscopy; electrons; exhibitions; free radicals; hydrogen; hydroxyl radicals; measurement; pigments; Show all 13 Subjects
- Abstract:
- ... Monascin, a specific type of monascus pigments, exhibits many bioactivities. In this study, the antioxidative activity of monascin was investigated by theoretical and experimental methods. First, the antioxidant potential of six monascus pigments was predicted by density functional theory (DFT) and time-dependent density functional theory (TDDFT) at the B3LYP/6-31+G (d, p) level, and monascus yell ...
- DOI:
- 10.1039/c9fo02410g
-
http://dx.doi.org/10.1039/c9fo02410g
- Author:
- Sun, Congcong; Wu, Xuefeng; Chen, Xiaoju; Li, Xingjiang; Zheng, Zhi; Jiang, Suwei
- Source:
- Food chemistry 2020 v.316 pp. 126243
- ISSN:
- 0308-8146
- Subject:
- Monascus purpureus, etc ; citrinin; cleavage (chemistry); culture media; dietary fiber; hydrogen bonding; liquid state fermentation; oils; okara; oligosaccharides; pigments; polysaccharides; scanning electron microscopy; swelling (materials); water holding capacity; Show all 15 Subjects
- Abstract:
- ... Okara dietary fiber was prepared by liquid fermentation with Monascus anka (M. anka). Infrared spectra results indicated that there were more oligosaccharides because of the hydrogen bond cleavage of the polysaccharides in okara Monascus dietary fiber (OMDF). Scanning electron microscopy and X-ray analyses showed that the structures of OMDF were altered as compared to that of the control. The UV–v ...
- DOI:
- 10.1016/j.foodchem.2020.126243
-
https://dx.doi.org/10.1016/j.foodchem.2020.126243
- Author:
- Guo, Na; Zhu, Ya-Wei; Jiang, Yi-Wei; Li, Hong-Kun; Liu, Zhi-Ming; Wang, Wei; Shan, Chun-Hua; Fu, Yu-Jie
- Source:
- Industrial crops and products 2020 v.148 pp. 112287
- ISSN:
- 0926-6690
- Subject:
- Monascus purpureus, etc ; alpha-glucosidase; antimicrobial properties; antioxidant activity; edible fungi; enzyme activity; enzyme inhibition; free radical scavengers; glycosides; kaempferol; leaves; mulberries; phenolic compounds; quercetin; solid state fermentation; Show all 15 Subjects
- Abstract:
- ... Mulberry leaves contain various types of phenolics, especially glycosides of the flavonoids quercetin and kaempferol. The aim of the present study was to investigate the production of quercetin and kaempferol as well as the biological activity of mulberry leaves with solid-state fermentation by edible fungi. Among the test fungi, the fermentation with Monascus anka was found to obviously increase ...
- DOI:
- 10.1016/j.indcrop.2020.112287
-
https://dx.doi.org/10.1016/j.indcrop.2020.112287