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- Neumann, Yvonne, et al. Show all 9 Authors
- Archives of microbiology 2015 v.197 no.2 pp. 245-267
- Staphylococcus aureus; fatty acids; humans; mutants; nose; physiology; pleiotropy; proteome; regulon; toxins; transcriptome; transcriptomics; virulence
- ... Staphylococcus aureus is a commensal of the human nose and skin. Human skin fatty acids, in particular cis-6-hexadecenoic acid (C-6-H), have high antistaphylococcal activity and can inhibit virulence determinant production. Here, we show that sub-MIC levels of C-6-H result in induction of increased resistance. The mechanism(s) of C-6-H activity was investigated by combined transcriptome and proteo ...
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