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- Nosyreva, Elena D., et al. Show all 12 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2007 v.104 no.7 pp. 2525-2530
- abnormal development; cleft palate; electrical properties; ion channels; mice; neurons; synapse; synaptic transmission; transcription (genetics)
- ... CASK is an evolutionarily conserved multidomain protein composed of an N-terminal Ca²⁺/calmodulin-kinase domain, central PDZ and SH3 domains, and a C-terminal guanylate kinase domain. Many potential activities for CASK have been suggested, including functions in scaffolding the synapse, in organizing ion channels, and in regulating neuronal gene transcription. To better define the physiological im ...
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