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- Oh, Sea-Jin, et al. Show all 16 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2013 v.110 no.8 pp. 3041-3046
- CD8-positive T-lymphocytes; Human adenovirus C; Human immunodeficiency virus; Langerhans cells; cell adhesion; cold; cytokines; dermis; epithelial cells; image analysis; immune response; immunization; nucleic acids; pathogens; protein structure; transcription (genetics); viral vaccines; viruses
- ... Stabilization of virus protein structure and nucleic acid integrity is challenging yet essential to preserve the transcriptional competence of live recombinant viral vaccine vectors in the absence of a cold chain. When coupled with needle-free skin delivery, such a platform would address an unmet need in global vaccine coverage against HIV and other global pathogens. Herein, we show that a simple ...
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