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- Ovchinnikov, Vladimir Y., et al. Show all 5 Authors
- Molecular biology reports 2018 v.45 no.6 pp. 1937-1945
- DDT (pesticide); animal ovaries; endometrium; females; humans; insecticides; liver; mammary glands; mechanism of action; messenger RNA; microRNA; rats; receptors
- ... A non-genotoxic insecticide dichlorodiphenyltrichloroethane (DDT), can affect mRNA and microRNA levels, however, its precise mechanism of action remains poorly understood. Using in silico methods we found that the rat miR-190 family is potentially regulated by CAR and ER receptors activated by DDT. We showed that exposure to DDT results in a dose- and organ-dependent increase in the expression of ...
- Ovchinnikov, Vladimir Y., et al. Show all 3 Authors
- Parasitology international 2017 v.66 no.6 pp. 773-776
- Clonorchis sinensis; Opisthorchis viverrini; animal development; biomarkers; blood; data collection; liver flukes; microRNA; parasitoses; regulator genes
- ... MicroRNAs (miRNAs) are important gene regulators that are key players in animal development and diseases. They are excreted in extracellular vesicles and because they were shown to be taken up by host cells they have been proposed as mediators of parasite-host communication, and potential biomarkers for the detection of parasitic infections from host blood. Consequently, it is crucial to precisely ...