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- Plaçais, Pierre-Yves, et al. Show all 11 Authors
- Cell 2019 v.178 no.4 pp. 901-918.e16
- Drosophila melanogaster; carbohydrate metabolism; carbohydrates; citrates; enterocytes; food intake; gender differences; invertebrates; males; sex reversal; sexual dimorphism; spermatogenesis; spermatozoa
- ... Physiology and metabolism are often sexually dimorphic, but the underlying mechanisms remain incompletely understood. Here, we use the intestine of Drosophila melanogaster to investigate how gut-derived signals contribute to sex differences in whole-body physiology. We find that carbohydrate handling is male-biased in a specific portion of the intestine. In contrast to known sexual dimorphisms in ...
- Plaçais, Pierre-Yves, et al. Show all 2 Author
- Science 2013 v.339 no.6118 pp. 440-442
- Drosophila; brain; energy; food deprivation; food shortages; hunger; memory; protein synthesis; starvation
- ... Hunger and Memory During starvation, are all brain functions slowed down, or are specific functions disabled to save energy? Plaçais and Preat (p. 440) investigated how the brain of Drosophila deals with severe resource limitation. The brain cut selected expenses to reduce the threat to survival and switched off the formation of aversive long-term memory that depends on costly protein synthesis. H ...
- Placais, Pierre-Yves, et al. Show all 9 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2015 v.112 no.2 pp. 578-583
- Drosophila; brain; dopamine; memory; neurons; nutritive value; starvation; sugars; taste; temporal variation
- ... Drosophila melanogaster can acquire a stable appetitive olfactory memory when the presentation of a sugar reward and an odor are paired. However, the neuronal mechanisms by which a single training induces long-term memory are poorly understood. Here we show that two distinct subsets of dopamine neurons in the fly brain signal reward for short-term (STM) and long-term memories (LTM). One subset ind ...
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