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1. First description of natural concomitant infection of avian nephritis virus and infectious bronchitis virus reveals exacerbated inflammatory response and renal damage in broiler chicks

Author:
Puvvala, Bhavani,   et al.   ; Munuswamy, Palanivelu; Ramakrishnan, Saravanan; Latheef, Shyma K.; Kappala, Deepthi; Mariappan, Asok Kumar; Kaore, Megha; Anbazhagan, Karthikeyan; Singh, Karam Pal; Dhama, Kuldeep;     Show all 10 Authors
Source:
Microbial pathogenesis 2021 v.154 pp. 104830
ISSN:
0882-4010
Subject:
; Avastrovirus 2; Avian nephritis virus; Infectious bronchitis virus; RNA-directed RNA polymerase; genes; glycoproteins; histopathology; inflammation; interleukin-12; interleukin-13; interleukin-4; macrophages; mixed infection; necropsy; pathogenesis; viruses
Abstract:
... We describe the first report on spontaneous Avian Nephritis Virus (ANV) and Infectious Bronchitis Virus (IBV) concurrent infection in broiler chicks. On necropsy, the kidneys were found swollen with its parenchyma and ureters stuffed with urate flakes. Histopathologically, the renal tubular damage and inflammatory response were severe in concurrently infected birds compared to the cases infected o ...
DOI:
10.1016/j.micpath.2021.104830